Publications related to Metabolome

Direct photolysis of human metabolites of the antibiotic sulfamethoxazole: Evidence for abiotic back-transformation

Tamar Kohn, Florence Bonvin, Julien Omlin, Rebecca Rutler, Timothy Strathmann

The presence of potentially persistent and bioactive human metabolites in surface waters gives rise to concern; yet little is known to date about the environmental fate of these compounds. This work investigates the direct photolysis of human metabolites o ...

Amer Chemical Soc2013

Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T

Rolf Gruetter, Lijing Xin, Cristina Ramona Cudalbu, Benoît Schaller

The broad resonances underlying the entire (1) H NMR spectrum of the brain, ascribed to macromolecules, can influence metabolite quantification. At the intermediate field strength of 3 T, distinct approaches for the determination of the macromolecule signa ...

Wiley-Blackwell2013

Integrated Biosensors for Personalized Medicine

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Cristina Boero, Camilla Baj-Rossi

Biosensors are heterogenous devices, incorporating biological struc- tures combined with electronics, optical or other readout systems. They have been developed for detecting different biomolecules and/or pathogens and represent a key technology for advanc ...

Ieee2012

Multiwalled Carbon Nanotubes for Amperometric Array-Based Biosensors

Giovanni De Micheli, Sandro Carrara, Irene Taurino

For diagnostic and therapeutic purposes an accurate determination of multiple metabolites is often required. Amperometric devices are attractive tools to quantify biological compounds due to the direct conversion of a biochemical event to a current. This r ...

2012

Single-Metabolite Bio-Nano-Sensors and System for Remote Monitoring in Animal Models

Giovanni De Micheli, Sandro Carrara, Eric Meurville, Cristina Boero, Andrea Cavallini, Léandre Bolomey

A novel system for remote monitoring of metabolism in animal model is proposed in this paper. The system is obtained by integrating Bio-Nano-Sensors to detect single- metabolites, an electrochemical front-end made with off- the-shelf components, an RF comm ...

Ieee Service Center, 445 Hoes Lane, Po Box 1331, Piscataway, Nj 08855-1331 Usa2011

New Technologies for Nanobiosensing and their Applications to Real-Time Monitoring

Giovanni De Micheli, Sandro Carrara, Cristina Boero

Amperometric biosensors are complex systems and they require a combination of technologies for their development. The aim of the present work is to exploit existing technologies for new purposes in order to develop nanostructured biosensors for the real-ti ...

2011

The metabolic footprint of aging in mice

Johan Auwerx, Kristina Schoonjans, Carlos Canto Alvarez, Pénélope Andreux, Raphaël Doenlen, Richardus Houtkooper, Ellen Helena Jeninga

Aging is characterized by a general decline in cellular function, which ultimately will affect whole body homeostasis. Although DNA damage and oxidative stress all contribute to aging, metabolic dysfunction is a common hallmark of aging at least in inverte ...

2011

Semisynthesis of fluorescent metabolite sensors on cell surfaces

Horst Vogel, Kai Johnsson, Luc Reymond, Rudolf Griss, Joachim Piguet, Matthias Albert Brun, Kui Thong Tan, Ruud Peters

Progress in understanding signal transduction and metabolic pathways is hampered by a shortage of suitable sensors for tracking metabolites, second messengers, and neurotransmitters in living cells. Here we introduce a class of rationally designed semisynt ...

2011

Targeted projection NMR spectroscopy for unambiguous metabolic profiling of complex mixtures

David Lyndon Emsley

Unambiguous identification of individual metabolites present in complex mixtures such as biofluids constitutes a crucial prerequisite for quantitative metabolomics, toward better understanding of biochemical processes in living systems. Increasing the dime ...

JOHN WILEY & SONS LTD2010

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Metabolome

Direct photolysis of human metabolites of the antibiotic sulfamethoxazole: Evidence for abiotic back-transformation

Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T

Integrated Biosensors for Personalized Medicine

Multiwalled Carbon Nanotubes for Amperometric Array-Based Biosensors

Single-Metabolite Bio-Nano-Sensors and System for Remote Monitoring in Animal Models

Integrated biosensing for diagnosis and therapy

New Technologies for Nanobiosensing and their Applications to Real-Time Monitoring

The metabolic footprint of aging in mice

Semisynthesis of fluorescent metabolite sensors on cell surfaces

Targeted projection NMR spectroscopy for unambiguous metabolic profiling of complex mixtures

Graph Chatbot

Chat with Graph Search

Integrated Biosensors for Personalized Medicine

New Technologies for Nanobiosensing and their Applications to Real-Time Monitoring

Direct photolysis of human metabolites of the antibiotic sulfamethoxazole: Evidence for abiotic back-transformation

Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T

Single-Metabolite Bio-Nano-Sensors and System for Remote Monitoring in Animal Models

Semisynthesis of fluorescent metabolite sensors on cell surfaces

Multiwalled Carbon Nanotubes for Amperometric Array-Based Biosensors

Integrated biosensing for diagnosis and therapy

The metabolic footprint of aging in mice

Targeted projection NMR spectroscopy for unambiguous metabolic profiling of complex mixtures