Concept
Confocal microscopy
Related publications (921)
Compact and effective photon-resolved image scanning microscope
Fluorescence confocal laser-scanning microscopy (LSM) is one of the most popular tools for life science research. This popularity is expected to grow thanks to single-photon array detectors tailored for LSM. These detectors offer unique single-photon spati ...
Spie-Soc Photo-Optical Instrumentation Engineers2024The multimodality cell segmentation challenge: toward universal solutions
Sahand Jamal Rahi, Vojislav Gligorovski, Marco Labagnara, Jun Ma, Xin Yang, Maxime Emmanuel Scheder, Yao Zhang, Bo Wang, Yixin Wang, Lin Han
Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in different experimen ...
Nature Portfolio2024Surface passivation and functionalisation for mass photometry
Suliana Manley, Jenny Sülzle, Laila Abdelaziz Abdelmoniem Elfeky
Interferometric scattering (iSCAT) microscopy enables the label-free observation of biomolecules. Consequently, single-particle imaging and tracking with the iSCAT-based method known as mass photometry (MP) is a growing area of study. However, establishing ...
Wiley2024Label-Free Techniques for Probing Biomolecular Condensates
Aleksandra Radenovic, Wayne Yang Wen Wei, Khalid Ashraf Mohie Ibrahim, Helena Miljkovic, Akhil Sai Naidu
Biomolecular condensates play important roles in a wide array of fundamental biological processes, such as cellular compartmentalization, cellular regulation, and other biochemical reactions. Since their discovery and first observations, an extensive and e ...
Amer Chemical Soc2024Fluorescence microscopy: A statistics-optics perspective
Fundamental properties of light unavoidably impose features on images collected using fluorescence microscopes. Accounting for these features is often critical in quantitatively interpreting microscopy images, especially those gathering information at scal ...
Amer Physical Soc2024Ghost imaging using two SPAD array detectors: a parameter study towards the realization of a 3D quantum microscope
Edoardo Charbon, Claudio Bruschini, Paul Mos, Yang Lin
Quantum ghost imaging can be an important tool in making optical measurements. One of the most useful aspects of ghost imaging is the unique ability to correlate two sets of independently collected information. We aim to use the principles of ghost imaging ...
Spie-Int Soc Optical Engineering2024Subsurface fluorescence time-of-flight imaging using a large-format single-photon avalanche diode sensor for tumor depth assessment
Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü, Yichen Feng
Significance: Fluorescence guidance is used clinically by surgeons to visualize anatomical and/or physiological phenomena in the surgical field that are difficult or impossible to detect by the naked eye. Such phenomena include tissue perfusion or molecula ...
Spie-Soc Photo-Optical Instrumentation Engineers2024Advances in High-Speed, Multiparametric Atomic Force Microscopy
After decades of technological advancements, high-speed atomic force microscopy (HS-AFM) has emerged as a powerful technique for visualizing dynamic processes. At the nanoscale, the AFM provides valuable insights into the sample by sensing minute interacti ...
EPFL2024Polydopamine-coated photoautotrophic bacteria for improving extracellular electron transfer in living photovoltaics
Ardemis Anoush Boghossian, Melania Reggente, Mohammed Mouhib, Hanxuan Wang, Charlotte Elisabeth Marie Roullier, Fabian Fischer, Patricia Brandl
Living photovoltaics are microbial electrochemical devices that use whole cell–electrode interactions to convert solar energy to electricity. The bottleneck in these technologies is the limited electron transfer between the microbe and the electrode surfac ...
2024Rescue of secretion of rare-disease-associated misfolded mutant glycoproteins in UGGT1 knock-out mammalian cells
Endoplasmic reticulum (ER) retention of misfolded glycoproteins is mediated by the ER-localized eukaryotic glycoprotein secretion checkpoint, UDP-glucose glycoprotein glucosyl-transferase (UGGT). The enzyme recognizes a misfolded glycoprotein and flags it ...
Hoboken2024