Concept

Organ (biology)

Related publications (47)

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Diverse cell therapy approaches constitute prime developmental prospects for managing acute or degenerative cartilaginous tissue affections, synergistically complementing specific surgical solutions. Bone marrow stimulation (i.e., microfracture) remains a ...

2021

An objective comparison of detection and segmentation algorithms for artefacts in clinical endoscopy

Georges Wagnières, Xiaokang Wang, Sharib Ali

We present a comprehensive analysis of the submissions to the first edition of the Endoscopy Artefact Detection challenge (EAD). Using crowd-sourcing, this initiative is a step towards understanding the limitations of existing state-of-the-art computer vis ...

NATURE PUBLISHING GROUP2020

Causal inference with limited resources: proportionally-representative interventions

Mats Julius Stensrud, Aaron Leor Sarvet

Investigators often evaluate treatment effects by considering settings in which all individuals are assigned a treatment of interest, assuming that an unlimited number of treatment units are available. However, many real-life treatments are of limited supp ...

2020

Gene replacement therapy provides benefit in an adult mouse model of Leigh syndrome

Johan Auwerx

Mutations in nuclear-encoded mitochondrial genes are responsible for a broad spectrum of disorders among which Leigh syndrome is the most common in infancy. No effective therapies are available for this severe disease mainly because of the limited capabili ...

2020

Sad faces increase the heartbeat-associated interoceptive information flow within the salience network: a MEG study

Hyeongdong Park

The somatic marker hypothesis proposes that the cortical representation of visceral signals is a crucial component of emotional processing. No previous study has investigated the information flow among brain regions that process visceral information during ...

2019

An extended regulatory landscape drives Tbx18 activity in a variety of prostate-associated cell lineages

Christopher Chase Bolt, Soumya Negi

The evolutionarily conserved transcription factor, Tbx18, is expressed in a dynamic pattern throughout embryonic and early postnatal life and plays crucial roles in the development of multiple organ systems. Previous studies have indicated that this dynami ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

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In this study we present the first fish-gut-on-chip model. This model is based on the reconstruction of the intestinal barrier by culturing two intestinal cell lines from rainbow trout, namely epithelial RTgutGC and fibroblastic RTgutF, in an artificial mi ...

2019

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Size of organs/organisms is a polygenic trait. Many of the growth-regulatory genes constitute conserved growth signaling pathways. However, how these multiple genes are orchestrated at the systems level to attain the natural variation in size including sex ...

WILEY2019

Organs-on-chip monitoring: sensors and other strategies

Philippe Renaud, Sandro Carrara, Francesca Stradolini, Tugba Kilic, Fatemeh Navaee

As a paradigm shifting player of tissue engineering, organs-on-chips (OOCs) are considered to hold great potential for future “clinical trials on chip” as well as a step forward to design personalized medicine. Despite all ethical concerns raised by commun ...

2018

Ammonia toxicity: from head to toe?

Peter Ott, Veronika Rackayová

Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues. It is known that the toxic ramifications of ammonia primarily touch the brain and cause neurologica ...

Springer Verlag2017