Byzantine EmpireThe Byzantine Empire, also referred to as the Eastern Roman Empire, was the continuation of the Roman Empire primarily in its eastern provinces during Late Antiquity and the Middle Ages, when its capital city was Constantinople. It survived the fall of the Western Roman Empire in the 5th century AD and continued to exist until the fall of Constantinople to the Ottoman Empire in 1453. During most of its existence, the empire remained the most powerful economic, cultural, and military force in the Mediterranean world.
ChangdeChangde ( chang2.de2) is a prefecture-level city in the northwest of Hunan province, People's Republic of China. In addition to the urban districts, Changde also administers the county-level city of Jinshi and six counties. Changde is adjacent to Dongting Lake to the east, the city of Yiyang to the south, Wuling and Xuefeng Mountains to the west, and Hubei province to the north. The area has been inhabited by humans since around 8,000 years ago. In that time, the city has changed names several times, but it has been known as Changde since the 12th century.
Tetracycline antibioticsTetracyclines are a group of broad-spectrum antibiotic compounds that have a common basic structure and are either isolated directly from several species of Streptomyces bacteria or produced semi-synthetically from those isolated compounds. Tetracycline molecules comprise a linear fused tetracyclic nucleus (rings designated A, B, C and D) to which a variety of functional groups are attached. Tetracyclines are named after their four ("tetra-") hydrocarbon rings ("-cycl-") derivation ("-ine").
Plague (disease)Plague is an infectious disease caused by the bacterium Yersinia pestis. Symptoms include fever, weakness and headache. Usually this begins one to seven days after exposure. There are three forms of plague, each affecting a different part of the body and causing associated symptoms. Pneumonic plague infects the lungs, causing shortness of breath, coughing and chest pain; bubonic plague affects the lymph nodes, making them swell; and septicemic plague infects the blood and can cause tissues to turn black and die.
TularemiaTularemia, also known as rabbit fever, is an infectious disease caused by the bacterium Francisella tularensis. Symptoms may include fever, skin ulcers, and enlarged lymph nodes. Occasionally, a form that results in pneumonia or a throat infection may occur. The bacterium is typically spread by ticks, deer flies, or contact with infected animals. It may also be spread by drinking contaminated water or breathing in contaminated dust. It does not spread directly between people. Diagnosis is by blood tests or cultures of the infected site.
RodentRodents (from Latin rodere, 'to gnaw') are mammals of the order Rodentia (rouˈdEnS@), which are characterized by a single pair of continuously growing incisors in each of the upper and lower jaws. About 40% of all mammal species are rodents. They are native to all major land masses except for New Zealand, Antarctica, and several oceanic islands, though they have subsequently been introduced to most of these land masses by human activity.
Yersinia pestisYersinia pestis (Y. pestis; formerly Pasteurella pestis) is a gram-negative, non-motile, coccobacillus bacterium without spores that is related to both Yersinia enterocolitica and Yersinia pseudotuberculosis, the pathogen from which Y. pestis evolved and responsible for the Far East scarlet-like fever. It is a facultative anaerobic organism that can infect humans via the Oriental rat flea (Xenopsylla cheopis). It causes the disease plague, which caused the Plague of Justinian and the Black Death, the deadliest pandemic in recorded history.
FeodosiaFeodosia (Феодо́сія, Теодо́сія, Feodosiia, Teodosiia; Феодосия, Feodosiya), also called in English Theodosia (from Θεοδοσία), is a town of regional significance on the Crimean coast of the Black Sea. Feodosia serves as the administrative center of Feodosia Municipality, one of the regions into which Crimea is divided. During much of its history, the city was known as Caffa (Ligurian: Cafà; Crimean Tatar and Kefe) or Kaffa. According to the 2014 census, its population was 69,145.
MarseilleMarseille (mɑːrˈseɪ , maʁsɛj, maχˈsɛjə; also spelled in English as Marseilles) is the prefecture of the French department of Bouches-du-Rhône and capital of the Provence-Alpes-Côte d'Azur region. Situated in the Provence region of southern France, it is located on the coast of the Gulf of Lion, part of the Mediterranean Sea, near the mouth of the Rhône river. Its occupants are called Marseillais.. Marseille is the second most populous city in France, with 870,321 inhabitants in 2020 (Jan.
Genghis KhanGenghis Khan (born Temüjin; 1162 – 25 August 1227), also known as Chinggis Khan, was the founder and first khagan of the Mongol Empire, which later became the largest contiguous land empire in history. Having spent the majority of his life uniting the Mongol tribes, he launched a series of military campaigns that conquered large parts of China and Central Asia. Born between 1155 and 1167 and given the name Temüjin, he was the oldest child of Yesugei, a Mongol chieftain of the Borjigin clan, and his wife Hoelun of the Olkhonud clan.
