ShinglesShingles, also known as zoster or herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area. Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. Two to four days before the rash occurs there may be tingling or local pain in the area. Other common symptoms are fever, headache, and tiredness. The rash usually heals within two to four weeks; however, some people develop ongoing nerve pain which can last for months or years, a condition called postherpetic neuralgia (PHN).
Cotton MatherCotton Mather (ˈmæðər; February 12, 1663 – February 13, 1728) was a New England Puritan clergyman and writer. Educated at Harvard College, in 1685 he joined his father Increase as minister of the Congregationalist Old North Meeting House of Boston, where he continued to preach for the rest of his life. A major intellectual and public figure in English-speaking colonial America, Cotton Mather helped lead the successful revolt of 1689 against Sir Edmund Andros, the governor imposed on New England by King James II.
Shunzhi EmperorThe Shunzhi Emperor (Fulin; 15 March 1638 – 5 February 1661) was the second emperor of the Qing dynasty of China, and the first Qing emperor to rule over China proper, reigning from 1644 to 1661. A committee of Manchu princes chose him to succeed his father, Hong Taiji (1592–1643), in September 1643, when he was five years old. The princes also appointed two co-regents: Dorgon (1612–1650), the 14th son of the Qing dynasty's founder Nurhaci (1559–1626), and Jirgalang (1599–1655), one of Nurhaci's nephews, both of whom were members of the Qing imperial clan.
Asymptomatic carrierAn asymptomatic carrier is a person or other organism that has become infected with a pathogen, but shows no signs or symptoms. Although unaffected by the pathogen, carriers can transmit it to others or develop symptoms in later stages of the disease. Asymptomatic carriers play a critical role in the transmission of common infectious diseases such as typhoid, HIV, C. difficile, influenzas, cholera, tuberculosis and COVID-19, although the last is often associated with "robust T-cell immunity" in more than a quarter of patients studied.
Biological agentA biological agent (also called bio-agent, biological threat agent, biological warfare agent, biological weapon, or bioweapon) is a bacterium, virus, protozoan, parasite, fungus, or toxin that can be used purposefully as a weapon in bioterrorism or biological warfare (BW). In addition to these living or replicating pathogens, toxins and biotoxins are also included among the bio-agents. More than 1,200 different kinds of potentially weaponizable bio-agents have been described and studied to date.
VaccinationVaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating the body's adaptive immunity, they help prevent sickness from an infectious disease. When a sufficiently large percentage of a population has been vaccinated, herd immunity results. Herd immunity protects those who may be immunocompromised and cannot get a vaccine because even a weakened version would harm them.
African trypanosomiasisAfrican trypanosomiasis, also known as African sleeping sickness or simply sleeping sickness, is an insect-borne parasitic infection of humans and other animals. It is caused by the species Trypanosoma brucei. Humans are infected by two types, Trypanosoma brucei gambiense (TbG) and Trypanosoma brucei rhodesiense (TbR). TbG causes over 92% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas.
TlatoaniTlatoani (tlahtoāni t͡ɬaʔtoˈaːniˀ, "one who speaks, ruler"; plural tlahtohque t͡ɬaʔˈtoʔkee̥ or tlatoque) is the Classical Nahuatl term for the ruler of an āltepētl, a pre-Hispanic state. It is the noun form of the verb "tlahtoa" meaning "speak, command, rule". As a result, it has been variously translated in English as "king", "ruler", or "speaker" in the political sense. Above a tlahtoani is the Huey Tlahtoani, sometimes translated as "Great Speaker", though more usually as "Emperor" (the term is often seen as the equivalent to the European "great king").
Immunity (medical)In biology, immunity is the state of being insusceptible or resistant to a noxious agent or process, especially a pathogen or infectious disease. Immunity may occur naturally or be produced by prior exposure or immunization. The immune system has innate and adaptive components. Innate immunity is present in all metazoans, immune responses: inflammatory responses and phagocytosis. The adaptive component, on the other hand, involves more advanced lymphatic cells that can distinguish between specific "non-self" substances in the presence of "self".
Antiviral drugAntiviral drugs are a class of medication used for treating viral infections. Most antivirals target specific viruses, while a broad-spectrum antiviral is effective against a wide range of viruses. Antiviral drugs are one class of antimicrobials, a larger group which also includes antibiotic (also termed antibacterial), antifungal and antiparasitic drugs, or antiviral drugs based on monoclonal antibodies. Most antivirals are considered relatively harmless to the host, and therefore can be used to treat infections.
