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The influence of substrate compn. on the yield, nature, and compn. of exopolysaccharides (EPS) produced by the food-grade strain G. xylinus I-2281 was investigated during controlled cultivations on mixed substrates contg. acetate and either glucose, sucros ...
PURPOSE: To investigate the potential use of polymeric nanoparticles for the delivery of antisense oligonucleotides in HIV-1-infected cell cultures. METHODS: Phosphorothioate oligonucleotides were encapsulated into poly (D,L-lactic acid) nanoparticles. Two ...
This report describes the synthesis and supramolecular organization of a novel class of linear-dendritic block copolymers. The molecules, which are termed rodcoil dendrons, consist of a cholesterol moiety that is attached to L-lysine dendrons of three diff ...
TThe synthesis and properties of a novel set of building blocks for the preparation of self-assembling biomaterials are described. These molecules consist of a relatively short oligo(L-lactic acid)n segment (n̄ = 10-40) that is substituted with a cholester ...
Crabtree neg. organisms such as Kluyveromyces, Pichia, Hansenula and Candida, are used to make selected org. products such as lactic acid. The organisms are cultured in a first culture medium that includes glucose, under conditions that promote cellular re ...
Formation of racemic pentose-2,4-bisphosphates is demonstrated, starting from glycolaldehyde phosphate and glyceraldehyde-2-phosphate, and induced by mixed valence double layer metal hydroxide minerals. The reactions proceed from dil. aq. reactant solns. ( ...
The formation of 4-hydroxy-2,5-dimethyl-3(2H)-furanone (HDMF) and 2(or 5)-ethyl-4-hydroxy-5(or 2)-methyl-3(2H)-furanone (EHMF) from pentose sugars was studied in Maillard model systems. The amts. generated at 90 DegC for 1 h were detd. by isotope diln. ass ...
A new class of molecules for the preparation of self-assembling biomaterials were synthesized. These molecules consist of a cholesteryl-moiety attached via an oligo(ethylene oxide) or oligo(L-lactic acid) segment to a biologically relevant headgroup. The o ...
Astrocytes appear to be ideally localized to couple neuronal activity to energy metabolism. First, specialized processes, the astrocytic end-feet surround blood vessels, the source of glucose for the brain. Second, other processes ensheath synapses and exp ...
Under particular circumstances like lactation and fasting, the blood-borne monocarboxylates acetoacetate, beta-hydroxybutyrate, and lactate represent significant energy substrates for the brain. Their utilization is dependent on a transport system present ...
