Concept

Upper motor neuron

Related publications (233)

Keeping track of sound objects in space: The contribution of early-stage auditory areas

The influential dual-stream model of auditory processing stipulates that information pertaining to the meaning and to the position of a given sound object is processed in parallel along two distinct pathways, the ventral and dorsal auditory streams. Functi ...

2018

Data-driven reconstruction of a point neuron mouse brain

Csaba Erö

In this work, we present a semi-automatic method to reconstruct a mouse whole-brain model at the point-neuron level by integrating a wide array of biological data. Our process has three parts: cell position and type assignment, connectivity mapping, and si ...

EPFL2018

Upper stimulation threshold for retinal ganglion cell activation

Diego Ghezzi

Objective. The existence of an upper threshold in electrically stimulated retinal ganglion cells (RGCs) is of interest because of its relevance to the development of visual prosthetic devices, which are designed to restore partial sight to blind patients. ...

2018

A sensory information compliant spinal cord stimulation system for the rehabilitation of motor functions

Silvestro Micera, Grégoire Courtine, Marco Capogrosso, Emanuele Formento, Karen Minassian

The present invention refers to a system for stimulation of the spinal cord for the rehabilitation of motor function in subjects with spinal cord injury or other motor disorders. Said system comprises a programmable implantable pulse generator (IPG), opera ...

2018

Cortical Dynamics in Presence of Assemblies of Densely Connected Weight-Hub Neurons

Wulfram Gerstner, Moritz Deger, Hesam Setareh

Experimental measurements of pairwise connection probability of pyramidal neurons together with the distribution of synaptic weights have been used to construct randomly connected model networks. However, several experimental studies suggest that both wiri ...

Frontiers Research Foundation2017

Action Monitoring Cortical Activity Coupled to Submovements

José del Rocio Millán Ruiz, Michael Eric Anthony Pereira, Aleksander Sobolewski

Numerous studies have examined neural correlates of the human brain’s action-monitoring system during experimentally segmented tasks. However, it remains unknown how such a system operates during continuous motor output when no experimental time marker is ...

2017

The importance of neuronal networks for motor rehabilitation after a stroke

Friedhelm Christoph Hummel

Every year in Europe 1.5 million patients suffer a new stroke. Despite the further developments in acute therapy with nationwide stroke units, thrombolysis, thrombectomy and post-acute neurorehabilitation, only a small proportion of patients recover to a s ...

Springer Verlag2017

Rich cell-type-specific network topology in neocortical microcircuitry

Henry Markram, Eilif Benjamin Muller, Srikanth Ramaswamy, Michael Reimann, Idan Segev, Eyal Gal, Michael London

Uncovering structural regularities and architectural topologies of cortical circuitry is vital for understanding neural computations. Recently, an experimentally constrained algorithm generated a dense network reconstruction of a similar to 0.3-mm(3) volum ...

Nature Publishing Group2017

Interactions between the corticospinal tract and premotor-motor pathways in stroke recovery

Friedhelm Christoph Hummel

Background and Purpose-Brain imaging has continuously enhanced our understanding how different brain networks contribute to motor recovery after stroke. However, the present models are still incomplete and do not fit for every patient. The interaction betw ...

American Heart Association2017

Influencing axon regeneration after spinal cord injury

Mark Andrew Anderson

Spinal cord injury (SCI) results in a severing of axonal connections that leads to permanent sensorimotor deficits. In cases of incomplete injury, rehabilitation paradigms have been reported to be successful in improving behavioral outcome in humans with S ...

EPFL2017

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