Publications related to Nucleic acid double helix

NAR Breakthrough Article Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination

Matteo Dal Peraro, Alexandra Styliani Kalantzi

In meiotic DNA recombination, the Hop2-Mnd1 complex promotes Dmc1-mediated single-stranded DNA (ssDNA) invasion into homologous chromosomes to form a synaptic complex by a yet-unclear mechanism. Here, the crystal structure of Hop2-Mnd1 reveals that it form ...

Oxford University Press2015

Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold

Homing endonucleases are useful tools for genome modification because of their capability to recognize and cleave specifically large DNA targets. These endonucleases generate a DNA double strand break that can be repaired by the DNA damage response machine ...

American Society for Biochemistry and Molecular Biology2015

Influence of DNA Binding Dyes on Bare DNA Structure Studied with Atomic Force Microscopy

Giovanni Dietler, Aleksandr Benke, Aleksandre Japaridze, Sylvain Renevey

Fluorescent dyes are widely used for staining and visualization of DNA in optical microscopy based methods. Even though for some dyes the mechanism of binding is known, how this binding affects DNA remains poorly understood. Here we present a novel experim ...

American Chemical Society2015

Effects of physiological self-crowding of DNA on shape and biological properties of DNA molecules with various levels of supercoiling

Giovanni Dietler, Julien Dorier, Yannis Burnier, Fabrizio Benedetti, Andrzej Stasiak, Aleksandre Japaridze, Robert Sebastian Kwapich

DNA in bacterial chromosomes and bacterial plasmids is supercoiled. DNA supercoiling is essential for DNA replication and gene regulation. However, the density of supercoiling in vivo is circa twice smaller than in deproteinized DNA molecules isolated from ...

Oxford University Press2015

Double-Normal Pairs In Space

János Pach

A double-normal pair of a finite set S of points that spans R-d is a pair of points {p, q} from S such that S lies in the closed strip bounded by the hyperplanes through p and q perpendicular to pq. A double-normal pair {p, q} is strict if S \ {p,q} lies i ...

London Mathematical Society, Cambridge2015

A coiled coil switch mediates cold sensing by the thermosensory protein DesK

Matteo Dal Peraro, Luciano Andres Abriata, Thomas Lemmin

The thermosensor histidine kinase DesK from Bacillus subtilis senses changes in membrane fluidity initiating an adaptive response. Structural changes in DesK have been implicated in transmembrane signaling, but direct evidence is still lacking. On the basi ...

Wiley-Blackwell2015

Functional Dissection of Intersubunit Interactions in the EspR Virulence Regulator of Mycobacterium tuberculosis

Stewart Cole, Giovanni Dietler, Matteo Dal Peraro, Florence Pojer, Marco Stenta, Aleksandre Japaridze, Benjamin Blasco, Basile Isidore Martin Wicky

The nucleoid-associated protein EspR, a chromosome organizer, has pleiotropic effects on expression of genes associated with cell wall function and pathogenesis in Mycobacterium tuberculosis. In particular, EspR binds to several sites upstream of the espAC ...

Amer Soc Microbiology2014

mu ABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA

John Maddocks, Daiva Petkeviciute, Marco Pasi, Jonathan Mitchell

We present the results of microsecond molecular dynamics simulations carried out by the ABC group of laboratories on a set of B-DNA oligomers containing the 136 distinct tetranucleotide base sequences. We demonstrate that the resulting trajectories have ex ...

Oxford Univ Press2014

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Nucleic acid double helix

NAR Breakthrough Article Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination

Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold

From polymers to gene regulation

Influence of DNA Binding Dyes on Bare DNA Structure Studied with Atomic Force Microscopy

Effects of physiological self-crowding of DNA on shape and biological properties of DNA molecules with various levels of supercoiling

Double-Normal Pairs In Space

A coiled coil switch mediates cold sensing by the thermosensory protein DesK

Research in the field of single biopolymers using scanning probe microscopy

Functional Dissection of Intersubunit Interactions in the EspR Virulence Regulator of Mycobacterium tuberculosis

mu ABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA

Graph Chatbot

Chat with Graph Search

mu ABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA

Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold

From polymers to gene regulation

NAR Breakthrough Article Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination

Double-Normal Pairs In Space

Research in the field of single biopolymers using scanning probe microscopy

Functional Dissection of Intersubunit Interactions in the EspR Virulence Regulator of Mycobacterium tuberculosis

Effects of physiological self-crowding of DNA on shape and biological properties of DNA molecules with various levels of supercoiling

A coiled coil switch mediates cold sensing by the thermosensory protein DesK

Influence of DNA Binding Dyes on Bare DNA Structure Studied with Atomic Force Microscopy