Publications related to Nucleic acid double helix

Toward an Effective Control of DNA's Submolecular Conformation on a Surface

Giovanni Dietler, Dusan Vobornik, Aleksandre Japaridze, Andrea Cerreta, Ewelina Wioletta Lipiec

DNA adopts different conformations based on its environment. We reveal conditions that either preserve the DNA's physiological B-conformation, even upon its placement in UHV, or lead to a partial B-form to A-form reorganization upon DNA's deposition on a s ...

American Chemical Society2016

X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair

Maria Josefina Marcaida Lopez

DNA duplexes containing unnatural base-pair surrogates are attractive biomolecular nanomaterials with potentially beneficial photophysical or electronic properties. Herein we report the first X-ray structure of a duplex containing a phen-pair in the center ...

Royal Soc Chemistry2016

Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies

Paul Joseph Dyson, Ursula Röthlisberger, Tina Riedel, Giulia Palermo, Thibaud Edouard Alistair von Erlach

Many transition metal complexes have unique physicochemical properties that can be efficiently exploited in medicinal chemistry for cancer treatment. Traditionally, double-stranded DNA has been assumed to be the main binding target; however, recent studies ...

2016

Preparation and Characterization of Stable -Synuclein Lipoprotein Particles

Henning Paul-Julius Stahlberg

Multiple neurodegenerative diseases are caused by the aggregation of the human -Synuclein (-Syn) protein. -Syn possesses high structural plasticity and the capability of interacting with membranes. Both features are not only essential for its physiological ...

American Society for Biochemistry & Molecular Biology (ASBMB)2016

Engineering the Selectivity of the DNA-SWCNT Sensor

Ardemis Anoush Boghossian, Alessandra Antonucci, Justyna Kupis-Rozmyslowicz

Single-walled carbon nanotubes (SWCNTs) demonstrate a unique combination of optical, chemical, and physical properties that render them suitable for a variety of sensing applications. Their photostable near-infrared (nIR) fluorescence emissions are highly ...

Electrochemical Soc Inc2016

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

Pierre Gönczy, Georgios Hatzopoulos, Paul Guichard

Centrioles are microtubule-based structures that play important roles notably in cell division and cilium biogenesis. CEP135/Bld10p family members are evolutionarily conserved microtubule-binding proteins important for centriole formation. Here, we analyze ...

Elsevier2016

Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation

Julien Dorier, Yannis Burnier, Fabrizio Benedetti, Andrzej Stasiak

Due to the helical structure of DNA the process of DNA replication is topologically complex. Freshly replicated DNA molecules are catenated with each other and are frequently knotted. For proper functioning of DNA it is necessary to remove all of these ent ...

Oxford University Press2015

Analyzing ion distributions around DNA: sequence-dependence of potassium ion distributions from microsecond molecular dynamics

John Maddocks, Marco Pasi

Microsecond molecular dynamics simulations of B-DNA oligomers carried out in an aqueous environment with a physiological salt concentration enable us to perform a detailed analysis of how potassium ions interact with the double helix. The oligomers studied ...

Oxford University Press2015

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Nucleic acid double helix

Toward an Effective Control of DNA's Submolecular Conformation on a Surface

X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair

Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies

Preparation and Characterization of Stable -Synuclein Lipoprotein Particles

Engineering the Selectivity of the DNA-SWCNT Sensor

The number of double-normals in space

Microfluidic device and method for isolation of nucleic acids

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation

Analyzing ion distributions around DNA: sequence-dependence of potassium ion distributions from microsecond molecular dynamics

Graph Chatbot

Chat with Graph Search

Preparation and Characterization of Stable -Synuclein Lipoprotein Particles

Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation

The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding

The number of double-normals in space

Engineering the Selectivity of the DNA-SWCNT Sensor

Microfluidic device and method for isolation of nucleic acids

Toward an Effective Control of DNA's Submolecular Conformation on a Surface

Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies

X-ray structure of a lectin-bound DNA duplex containing an unnatural phenanthrenyl pair

Analyzing ion distributions around DNA: sequence-dependence of potassium ion distributions from microsecond molecular dynamics