Lectures related to Proteolysis

J-Domain Protein Specificity: Genetics Insights

Explores the genetic basis of J-domain protein specificity and the essential role of Sis1 in protein homeostasis.

Post-translational regulation of ER proteostasis

Explores the post-translational regulation of ER proteostasis, focusing on BiP chaperone activity, ER stress response, and FICD-mediated AMPylation.

Hsp70 Chaperone Binding: Substrate Selectivity and Function

Explores the selective promiscuity in binding of the E. coli Hsp70 chaperone to unfolded or misfolded protein substrates, examining its implications in protein folding mechanisms.