Concept

Hypoxemia

Related publications (32)

Moulding and Microfluidic Wet Spinning of the Soft Polymer Optical Fibers for Sensory Applications

Polymer optical fibre (POFs) based wearable sensors have attracted a lot of attention in the field of healthcare and biomedical applications. They are in particular envision as the next generation of sensors for the continuous, real-time n ...

EPFL2024

Modulation of Pulsatile Left Ventricular Afterload by Renal Denervation in Heart Failure With Preserved Ejection Fraction

Nikolaos Stergiopoulos, Stamatia Zoi Pagoulatou

Background:Arterial stiffening contributes to hemodynamic derangements in heart failure with preserved ejection fraction (HFpEF). We sought to investigate the impact of renal denervation on pulsatile left ventricular loading in patients with HFpEF and hype ...

Philadelphia2023

Hypoxia Conditioning as a Promising Therapeutic Target in Parkinson's Disease?

Hilal Lashuel, Grégoire Millet, Johannes Burtscher, Muhammed Muazzam Kamil Syed

Several lines of research point to a key role of low oxygen supply (hypoxia) in Parkinson's disease pathogenesis. Although severe hypoxia is detrimental for the brain, physiological adaptations to mild hypoxia are neuroprotective. Herein we discuss, how ne ...

WILEY2021

Oxygen availability in a HAPE-positive and a HAPE-negative woman before and during a visit to 3480 meters

Johannes Burtscher

Background: Testing the hypoxic ventilatory response (HVR) at low-altitude helps to detect those who do not hyperventilate appropriately in hypoxia but might not necessarily predict the HVR and the risk to develop acute mountain sickness (AMS) at high alti ...

ELSEVIER2020

Implementation and Calibration of a Deep Neural Network to Predict Parameters of Left Ventricular Systolic Function Based on Pulmonary and Systemic Arterial Pressure Signals

Simone Deparis, Luca Pegolotti, Jean Bonnemain

The evaluation of cardiac contractility by the assessment of the ventricular systolic elastance function is clinically challenging and cannot be easily obtained at the bedside. In this work, we present a framework characterizing left ventricular systolic f ...

2020

AltitudeOmics: Spontaneous Baroreflex Sensitivity During Acclimatization to 5,260 m: A Comparison of Methods

Jean-Marc Vesin, Sasan Yazdani

Introduction Baroreflex sensitivity (BRS) is essential to ensure rapid adjustment to variations in blood pressure (BP). Spontaneous baroreflex function can be assessed using continuous recordings of blood pressure. The goal of this study was to compare fou ...

FRONTIERS MEDIA SA2019

On the importance of the nonuniform aortic stiffening in the hemodynamics of physiological aging

Nikolaos Stergiopoulos, Bram Trachet, Vasiliki Bikia, Stamatia Zoi Pagoulatou

Mathematical models of the arterial tree constitute a valuable tool to investigate the hemodynamics of aging and pathology. Rendering such models as patient specific could allow for the assessment of central hemodynamic variables of clinical interest. Howe ...

AMER PHYSIOLOGICAL SOC2019

A 1D computer model of the arterial circulation in horses: An important resource for studying global interactions between heart and vessels under normal and pathological conditions

Nikolaos Stergiopoulos, Patrick Segers

Arterial rupture in horses has been observed during exercise, after phenylephrine administration or during parturition (uterine artery). In human pathophysiological research, the use of computer models for studying arterial hemodynamics and understanding n ...

2019

Sequential Bone-Marrow Cell Delivery of VEGFA/S1P Improves Vascularization and Limits Adverse Cardiac Remodeling After Myocardial Infarction in Mice

Michele De Palma, Mario Leonardo Squadrito, Magdalena Maria Zak

Microvascular dysfunction and resulting tissue hypoxia is a major contributor to the pathogenesis and evolution of cardiovascular diseases (CVD). Diverse gene and cell therapies have been proposed to preserve the microvasculature or boost angiogenesis in C ...

MARY ANN LIEBERT, INC2019

An inverse problem for a semilinear parabolic equation arising from cardiac electrophysiology

Andrea Manzoni

In this paper we develop theoretical analysis and numerical reconstruction techniques for the solution of an inverse boundary value problem dealing with the nonlinear, time-dependent monodomain equation, which models the evolution of the electric potential ...

Iop Publishing Ltd2017

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