Publications related to Kainic acid

A 16-Channel 1.1mm2 Implantable Seizure Control SoC with Sub-μW/Channel Consumption and Closed-Loop Stimulation in 0.18μm CMOS

Alexandre Schmid, Mahsa Shoaran, Yusuf Leblebici, Amirhossein Shahshahani, Masoud Shahshahani

We present a 16-channel seizure detection system-on-chip (SoC) with 0.92μW/channel power dissipation in a total area of 1.1mm² including a closed-loop neural stimulator. A set of four features are extracted from the spatially filtered neural data to achiev ...

IEEE2016

Astrocyte scar formation aids central nervous system axon regeneration

Mark Andrew Anderson, Michael V. Sofroniew

Transected axons fail to regrow in the mature central nervous system. Astrocytic scars are widely regarded as causal in this failure. Here, using three genetically targeted loss-of-function manipulations in adult mice, we show that preventing astrocyte sca ...

Nature Publishing Group2016

Interfacing a salamander brain with a salamander-like robot: Control of speed and direction with calcium signals from brainstem reticulospinal neurons

Auke Ijspeert, Robin Thandiackal

An important topic in designing neuroprosthetic devices for animals or patients with spinal cord injury is to find the right brain regions with which to interface the device. In vertebrates, an interesting target could be the reticulospinal (RS) neurons, w ...

IEEE2016

An Adeno-Associated Virus-Based Intracellular Sensor of Pathological Nuclear Factor-kappa B Activation for Disease-Inducible Gene Transfer

Elias Georges Gebara

Stimulation of resident cells by NF-kappa B activating cytokines is a central element of inflammatory and degenerative disorders of the central nervous system (CNS). This disease-mediated NF-kappa B activation could be used to drive transgene expression se ...

Public Library Science2013

High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice

Rolf Gruetter, Hongxia Lei, Malte Alf

After ischemic stroke, the ischemic damage to brain tissue evolves over time and with an uneven spatial distribution. Early irreversible changes occur in the ischemic core, whereas, in the penumbra, which receives more collateral blood flow, the damage is ...

Wiley-Blackwell2012

Microcircuits of excitatory and inhibitory neurons in layer 2/3 of mouse barrel cortex

Wulfram Gerstner, Carl Petersen, Céline Matéo, Michael Avermann, Christian Tomm

Avermann M, Tomm C, Mateo C, Gerstner W, Petersen CC. Microcircuits of excitatory and inhibitory neurons in layer 2/3 of mouse barrel cortex. J Neurophysiol 107: 3116-3134, 2012. First published March 7, 2012; doi:10.1152/jn.00917.2011.-Synaptic interactio ...

American Physiological Society2012

A neuron membrane mesh representation for visualization of electrophysiological simulations

Henry Markram, Felix Schürmann, Sean Lewis Hill, Juan Bautista Hernando Vieites, Sébastien Lasserre

We present a process to automatically generate three-dimensional mesh representations of the complex, arborized cell membrane surface of cortical neurons (the principal information processing cells of the brain) from nonuniform morphological measurements. ...

Institute of Electrical and Electronics Engineers2012

Cell death detection and ionic homeostasis monitoring with digital holographic microscopy

Pierre Magistretti, Christian Depeursinge, Nicolas Pavillon, Pierre Marquet, Jonas Kühn, Pascal Jourdain

Digital holographic microscopy is an interferometric technique enabling the measurement of the quantitative phase shifts induced by cell bodies. We correlate the phase signal measured on neurons with calcium imaging measured by fluorescence on cells loaded ...

SPIE2011

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Kainic acid

A 16-Channel 1.1mm2 Implantable Seizure Control SoC with Sub-μW/Channel Consumption and Closed-Loop Stimulation in 0.18μm CMOS

Astrocyte scar formation aids central nervous system axon regeneration

Interfacing a salamander brain with a salamander-like robot: Control of speed and direction with calcium signals from brainstem reticulospinal neurons

Serotonergic neurons signal reward and punishment on multiple timescales

An Adeno-Associated Virus-Based Intracellular Sensor of Pathological Nuclear Factor-kappa B Activation for Disease-Inducible Gene Transfer

High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice

Microcircuits of excitatory and inhibitory neurons in layer 2/3 of mouse barrel cortex

A neuron membrane mesh representation for visualization of electrophysiological simulations

Mathematical Modeling of Brain Energy Metabolism, Measured with PET and MRS in Rodents

Cell death detection and ionic homeostasis monitoring with digital holographic microscopy

Graph Chatbot

Chat with Graph Search

Serotonergic neurons signal reward and punishment on multiple timescales

Microcircuits of excitatory and inhibitory neurons in layer 2/3 of mouse barrel cortex

Astrocyte scar formation aids central nervous system axon regeneration

Interfacing a salamander brain with a salamander-like robot: Control of speed and direction with calcium signals from brainstem reticulospinal neurons

High-resolution spatial mapping of changes in the neurochemical profile after focal ischemia in mice

Mathematical Modeling of Brain Energy Metabolism, Measured with PET and MRS in Rodents

A neuron membrane mesh representation for visualization of electrophysiological simulations

Cell death detection and ionic homeostasis monitoring with digital holographic microscopy

A 16-Channel 1.1mm2 Implantable Seizure Control SoC with Sub-μW/Channel Consumption and Closed-Loop Stimulation in 0.18μm CMOS

An Adeno-Associated Virus-Based Intracellular Sensor of Pathological Nuclear Factor-kappa B Activation for Disease-Inducible Gene Transfer