Concept

Nucleic acid secondary structure

Related publications (135)

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Thick-film and LTCC (Low Temperature Cofired Ceramic) technologies find increasing use in meso-scale sensors, actuators and related devices that feature excellent dimensional, thermal and chemical stability at moderate cost. While several materials and pro ...

IMAPS2009

Scaling of double and single stranded DNA

Giovanni Dietler

Long double stranded DNA (DsDNA) and single stranded DNA (ssDNA) molecules were studied by direct imaging with the Atomic Force Microscope (AFM) in order to determine their scaling properties, exponents, distributions and persistence length in the frame wo ...

2009

The promotion of secondary structures in single-stranded DNA by drugs that bind to duplex DNA: an atomic force microscopy study

Giovanni Dietler, Guillaume Witz, Kristian Rechendorff

We study the behavior of single-stranded DNA (ssDNA) in the presence of well-known drugs with either an intercalating binding mode, such as daunorubicin, actinomycin D, and chloroquine, or a minor groove binding mode, such as netropsin and berenil, by atom ...

2008

Effects of N-terminus substitution on the structure and spectroscopy of gas-phase helices

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Because of the importance of helices in the secondary structure of proteins, we have undertaken a study of their spectroscopy, fragmentation patterns and conformations in the gas phase. In this work, we describe the effects of substitution at the N-terminu ...

2008

Hierarchical Image Registration with an Active Contour-Based Atlas Registration Model

Jean-Philippe Thiran, Valérie Duay, Subrahmanyam Venkata Ravi Mohana Sai Gorthi, Nawal Houhou

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2008

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Peptide based and peptide hybrid materials represent two interesting and challenging classes of biomaterials. Both classes consist of and contain, respectively, one or more polypeptide blocks, endowing the resulting polymers with enhanced self-assembly pro ...

EPFL2008

Supramolecular structures of polypeptides

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The formation of supramolecular structures is a central issue in bio- and nanotechnology and therein plays an important role for many novel developments such as biocompatible materials for integrating living cells or coating for implantable sensing devices ...

EPFL2008

Chemical approach for the study of the 'kissing complex' of Moloney murine leukaemia Virus

Sébastien Porcher

The replication of Moloney murine leukaemia virus relies on the formation of a stable homodimeric 'kissing complex' of a GACG tetraloop interacting through only two C center dot G base pairs flanked of 5'-adjacent Unpaired adenosines A9. Previous NMR inves ...

2008

Complementing structural information of modular proteins with small angle neutron scattering and contrast variation

Many macromolecules in the cell function by forming multi-component assemblies. We have applied the technique of small angle neutron scattering to study a nucleic acid-protein complex and a multi-protein complex. The results illustrate the versatility and ...

Springer Verlag2008

Optimized methods for the enzymatic ligation of oligoribonucleotides and analogues

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The preparation of oligoribonucleotides is of great interest for structural and functional investigations in biomolecular chemistry and biology. Relevant RNAs are relatively long and contain often modifications. Two methods for their preparation are curren ...

EPFL2006

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