Publications related to Sarcoma

Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression

Douglas Hanahan, Krisztian Homicsko, Mohammad Sadegh Saghafinia, Stephan Wullschleger, Iacovos Michael, Giovanni Ciriello

Pancreatic neuroendocrine tumors (PanNET) comprise two molecular subtypes, relatively benign islet tumors (IT) and invasive, metastasis-like primary (MLP) tumors. Until now, the origin of aggressive MLP tumors has been obscure. Herein, using multi-omics ap ...

AMER ASSOC CANCER RESEARCH2021

Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice

Matthias Lütolf, Michele De Palma, Alan Nicolas Thierry Guichard, Mauro Delorenzi, Mario Leonardo Squadrito, Sina Nassiri, Nikolche Gjorevski, Simone Ragusa, Borja Prat Luri, Laureline Wetterwald

Mutations in APC promote colorectal cancer (CRC) progression through uncontrolled WNT signaling. Patients with desmoplastic CRC have a significantly worse prognosis and do not benefit from chemotherapy, but the mechanisms underlying the differential respon ...

2020

Roadmap toward the 10 ps time-of-flight PET challenge

Edoardo Charbon, Mathieu Benoit, Christian Morel, Joao Varela

Since the seventies, positron emission tomography (PET) has become an invaluable medical molecular imaging modality with an unprecedented sensitivity at the picomolar level, especially for cancer diagnosis and the monitoring of its response to therapy. Mor ...

IOP PUBLISHING LTD2020

Intramuscular Follicular Lymphoma

Filipe Amândio Brandão Sanches Vong Martins

We present an interesting image of a painless growing mass of the right arm in a 76-year-old man. A musculoskeletal MRI of the right arm showed a 7.5 x 3-cm homogeneous, well-defined mass, elongated along the course of muscle fascias and independent of the ...

LIPPINCOTT WILLIAMS & WILKINS2018

Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes

Andrea Ferrari, Michela Casanova

Embryonal Rhabdomyosarcoma (ERMS) and Undifferentiated Pleomorphic Sarcoma (UPS) are distinct sarcoma subtypes. Here we investigate the relevance of the satellite cell (SC) niche in sarcoma development by using Hepatocyte Growth Factor (HGF) to perturb the ...

Elife Sciences Publications Ltd2016

Treatment of pleural malignancies by photo-induction combined to systemic chemotherapy: Proof of concept on rodent lung tumors and feasibility study on porcine chest cavities

Georges Wagnières, Michaël Bensimon, Elodie Debefve, Laurent Décosterd, Jean Yannis Perentes

Background: Low-dose, Visudyne (R)-mediated photodynamic therapy (photo-induction) was shown to selectively enhance tumor vessel transport causing increased uptake of systemically administered chemotherapy in various tumor types grown on rodent lungs. The ...

Wiley-Blackwell2015

Growth of osteosarcoma cells in a three-dimensional bone-like matrix alters their susceptibility to adeno-associated virus

Peter Martin Beard, Martha Luise Müller, Sangeeta Dey, Katarina Damjanovic

Osteosarcoma cells U2OS are partially susceptible to adeno-associated virus (AAV)-2 infection, allowing efficient synthesis of Rep proteins and, in a low percentage of cells, capsid production. It is not clear if this partial susceptibility to infection is ...

Soc General Microbiology2014

Vitamin D and energy homeostasis-of mice and men

Johan Auwerx, Kristina Schoonjans, Alessia Perino

The vitamin D endocrine system has many extraskeletal targets, including adipose tissue. 1,25-Dihydroxyvitamin D-3, the active form of vitamin D, not only increases adipogenesis and the expression of typical adipocyte genes but also decreases the expressio ...

Nature Publishing Group2014

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Sarcoma

A pan-cancer classification based on fmrp pathway activity that informs differential prognosis and therapeutic responses

Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression

Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice

Roadmap toward the 10 ps time-of-flight PET challenge

Intramuscular Follicular Lymphoma

Preventive chemotherapy to control soil-transmitted helminthiasis averted more than 500 000 DALYs in 2015

Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes

Treatment of pleural malignancies by photo-induction combined to systemic chemotherapy: Proof of concept on rodent lung tumors and feasibility study on porcine chest cavities

Growth of osteosarcoma cells in a three-dimensional bone-like matrix alters their susceptibility to adeno-associated virus

Vitamin D and energy homeostasis-of mice and men

Graph Chatbot

Chat with Graph Search

Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression

Preventive chemotherapy to control soil-transmitted helminthiasis averted more than 500 000 DALYs in 2015

Intramuscular Follicular Lymphoma

Growth of osteosarcoma cells in a three-dimensional bone-like matrix alters their susceptibility to adeno-associated virus

Treatment of pleural malignancies by photo-induction combined to systemic chemotherapy: Proof of concept on rodent lung tumors and feasibility study on porcine chest cavities

Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes

A pan-cancer classification based on fmrp pathway activity that informs differential prognosis and therapeutic responses

Roadmap toward the 10 ps time-of-flight PET challenge

Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice

Vitamin D and energy homeostasis-of mice and men