Publications related to Behçet's disease

Absence of specific alternatively spliced exon of CD44 in macrophages prevents colitis

CD44 is a transmembrane molecule appearing in numerous isoforms generated by insertions of alternatively spliced variant exons (CD44v) and having various binding partners. CD44v7 on T cells was proposed to promote colitis by preventing T-cell apoptosis. He ...

NATURE PUBLISHING GROUP2018

Peptide macrocycle inhibitor of coagulation factor XII with subnanomolar affinity and high target selectivity

Christian Heinis, Jonas Alfred Karl Wilbs, Simon Jan Middendorp

Factor XII (FXII) is a plasma protease that has emerged in recent years as a potential target to treat or prevent pathological thrombosis, to inhibit contact activation in extracorporeal circulation, and to treat the swelling disorder hereditary angioedema ...

2017

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

Jacques Rougemont, Laure Menin, Nicola Harris, Alessandra Piersigilli, Benjamin John Marsland, Mario Michael Zaiss, Ilaria Mosconi, Lalit Kumar Dubey, Alexis Rapin, Luc Xavier Marie Lebon, Andrew J. Macpherson

Intestinal helminths are potent regulators of their host's immune system and can ameliorate inflammatory diseases such as allergic asthma. In the present study we have assessed whether this anti-inflammatory activity was purely intrinsic to helminths, or w ...

Elsevier2015

The consensus molecular subtypes of colorectal cancer

Douglas Hanahan, Krisztian Homicsko, Sarah Gerster, Paolo Angelino, Mauro Delorenzi, Anguraj Sadanandam, Xin Wang

Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and drug responses. To resolve inconsistencies among the reported gene expression-based CRC classifications and facilitate clinical translation, we formed an international c ...

Nature Publishing Group2015

PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

Simona Frateschi, Friedrich Beermann, Anne Wilson, Roch-Philippe Charles

Altered serine protease activity is associated with skin disorders in humans and in mice. The serine protease channel-activating protease-1 (CAP1; also termed protease serine S1 family member 8 (Prss8)) is important for epidermal homeostasis and is thus in ...

2011

Design of a light delivery system for the photodynamic treatment of the Crohn's disease

Hubert van den Bergh, Georges Wagnières, Tanja Gabrecht, François André Borle

Crohn's disease is an inflammatory bowel disease originating from an overwhelming response of the mucosal immune system. Low dose photodynamic therapy (PDT) may modify the mucosal immune response and thus serve as a therapy for Crohn's disease. Most patien ...

2007

Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction

Françoise Gisou van der Goot Grunberg

Shigellosis is an acute inflammatory bowel disease caused by the enteroinvasive bacterium SHIGELLA: Upon host cell-Shigella interaction, major host cell signalling responses are activated. Deciphering the initial molecular events is crucial to understandin ...

2002

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Behçet's disease

Absence of specific alternatively spliced exon of CD44 in macrophages prevents colitis

Peptide macrocycle inhibitor of coagulation factor XII with subnanomolar affinity and high target selectivity

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

The consensus molecular subtypes of colorectal cancer

Is There a Need for Smooth Muscle Cell Transplantation in Urethral Reconstruction?

PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

Mathematical Modeling of T-Cell Experimental Data

Design of a light delivery system for the photodynamic treatment of the Crohn's disease

Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction

Graph Chatbot

Chat with Graph Search

Design of a light delivery system for the photodynamic treatment of the Crohn's disease

Peptide macrocycle inhibitor of coagulation factor XII with subnanomolar affinity and high target selectivity

Absence of specific alternatively spliced exon of CD44 in macrophages prevents colitis

The consensus molecular subtypes of colorectal cancer

Is There a Need for Smooth Muscle Cell Transplantation in Urethral Reconstruction?

Mathematical Modeling of T-Cell Experimental Data

Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction

PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation