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Drug development

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Drug development

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Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma

Genome-Scale Identification of Essential Metabolic Processes for Targeting the Plasmodium Liver Stage

MedCo: Enabling Secure and Privacy-Preserving Exploration of Distributed Clinical and Genomic Data

A design of experiment approach for efficient multi-parametric drug testing using a Caenorhabditis elegans model

Fluorescent Benzothiazinone Analogues Efficiently and Selectively Label Dpre1 in Mycobacteria and Actinobacteria

More Medicines for Tuberculosis: Fuelling Drug Discovery against Mycobacterium tuberculosis

Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis

Discovery of novel competitive dihydropteridine reductase inhibitors via high throughput screening and their effect on metabolic pterin balance of fibroblast.

Microfluidic high-content phenotypic screening on a Caenorhabditis elegans model

Development of cyclic peptide inhibitors of coagulation factor XII and matrix metalloproteinase 2