Concept

Rat-baiting

Related publications (24)

Development and applications of hyperpolarized 13C and 1H MR spectroscopy of cerebral metabolism at ultra-high field

This thesis is composed of four studies centered on investigating cerebral metabolism using magnetic resonance spectroscopy (MRS) of hyperpolarized and non-hyperpolarized compounds at ultra-high field. In the first two chapters, we studied longitudinally t ...

EPFL2021

Inhaling xenon ameliorates l -dopa-induced dyskinesia in experimental parkinsonism

Grégoire Courtine, Eduardo Martin Moraud, Tomislav Milekovic, Shiqi Sun

Parkinson's disease motor symptoms are treated with levodopa, but long‐term treatment leads to disabling dyskinesia. Altered synaptic transmission and maladaptive plasticity of corticostriatal glutamatergic projections play a critical role in the pathophys ...

2018

Photobiomodulation Suppresses Alpha-Synuclein-Induced Toxicity in an AAV-Based Rat Genetic Model of Parkinson's Disease

Hubert van den Bergh, Hilal Lashuel, Georges Wagnières, Blaise Lovisa, Abid Oueslati, John Perrin

Converging lines of evidence indicate that near-infrared light treatment, also known as photobiomodulation (PBM), may exert beneficial effects and protect against cellular toxicity and degeneration in several animal models of human pathologies, including n ...

Public Library of Science2015

Ex situ evaluation of the composition of protein corona of intravenously injected superparamagnetic nanoparticles in rats

Heinrich Hofmann, Marie-Gabrielle Chantal Brigitte Ollivier Beuzelin, Lionel André Maurizi, Morteza Mahmoudi, Usawadee Sakulkhu

It is now well recognized that the surfaces of nanoparticles (NPs) are coated with biomolecules (e. g., proteins) in a biological medium. Although extensive reports have been published on the protein corona at the surface of NPs in vitro, there are very fe ...

Royal Soc Chemistry2014

3D Printing of Rat Salivary Glands: The Submandibular-Sublingual Complex

Alessandro Daducci

The morphology and the functionality of the murid glandular complex, composed of the submandibular and sublingual salivary glands (SSC), were the object of several studies conducted mainly using magnetic resonance imaging (MRI). Using a 4.7 T scanner and a ...

Wiley-Blackwell2014

A Shape-Template Based Two-Stage Corpus Callosum Segmentation Technique for Sagittal Plane T1-Weighted Brain Magnetic Resonance Images

Michaël Unser, Chandra Sekhar Seelamantula

We propose a semi-automatic technique to segment corpus callosum (CC) using a two-stage snake formulation: A restricted affine transform (RAT) constrained snake followed by an unconstrained snake in an iterative fashion. A statistical model is developed to ...

IEEE2013

High-performance and reliable site-directed in vivo genetic manipulation of mouse and rat brain by in utero electroporation with a triple-electrode probe

Diego Ghezzi

One of the challenges for modern neuroscience is to understand the role of specific genes in the determination of cellular fate, and in the formation and physiology of neuronal-circuits. Techniques for genetic manipulation in vivo such as in utero electrop ...

2013

Neurobiological Mechanisms Involved in the Establishment and Maintenance of Dominance Hierarchies and its Modulation by Stress in Rats

Maria del Carmen Sandi Perez, Marjan Timmer

Stress can have a strong and long lasting effect on the establishment and maintenance of dominance hierarchies in rats. When two rats of a pair have not been stressed (non-stressed pair) before a first social encounter, they establish a dominance hierarchy ...

EPFL2011

Feasibility of in vivo N-15 MRS detection of hyperpolarized N-15 labeled choline in rats

Rolf Gruetter, Cristina Ramona Cudalbu, Arnaud Comment, Sami Jannin, Ruud van Heeswijk, Fiodar Kurdzesau

The increase of total choline in tumors has become an important biomarker in cancer diagnosis. Choline and choline metabolites can be measured in vivo and in vitro using multinuclear MRS. Recent in vivo C-13 MRS studies using labeled substrates enhanced vi ...

2010

Direct localised measurement of electrical resistivity profile in rat and embryonic chick retinas using a microprobe

Philippe Renaud, Arnaud Bertsch, Harald Van Lintel, Robert Meissner, Sri Harsha Kasi Raj

We report an alternative technique to perform a direct and local measurement of electrical resistivities in a layered retinal tissue. Information on resistivity changes along the depth in a retina is important for modelling retinal stimulation by retinal p ...

University of Oslo2010

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