Concept

Adipose tissue

Related publications (358)

The Exchangeable Apolipoprotein Nplp2 Sustains Lipid Flow and Heat Acclimation in Drosophila

Bruno Lemaitre, Jean Philippe Boquete, Samuel Rommelaere, Jérémie Piton

In ectotherms, increased ambient temperature requires the organism to consume substantial amounts of energy to sustain a higher metabolic rate, prevent cellular damage, and respond to heat stress. Here, we identify a heat-inducible apolipoprotein required ...

CELL PRESS2019

Teaching measurement techniques in biomechanics through inquiry-based labs

Dominique Pioletti, Pierre-Etienne Bourban, Siara Ruth Isaac, Cécile Hardebolle, Oriane Poupart

Inquiry-based labs seek to engage students in an authentic process of scientific inquiry, where students pose and invest scientific questions. The effect of inquiry-based labs has consistently been found to be positive [1]. In addition, the results of Furt ...

2019

Methods of derivation and/or propagation of epithelial cells

Yann Barrandon, Andrea Zaffalon

The present invention relates to methods of derivation and/or propagation of epithelial cells from tissue comprising culturing said tissue in media containing an effective amount of a proprotein convertase inhibitor for a period of time allowing the deriva ...

2018

Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population

Johan Auwerx, Jun Yong Kim, Dongryeol Ryu, Evan Graehl Williams, Pooja Jha, Jiayi Lan, Ruedi Aebersold, Moaraj Hasan

We have used SWATH mass spectrometry to quantify 3648 proteins across 76 proteomes collected from genetically diverse BXD mouse strains in two fractions (mitochondria and total cell) from five tissues: liver, quadriceps, heart, brain, and brown adipose (BA ...

AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC2018

Rhythms of the Genome: Circadian Dynamics from Chromatin Topology, Tissue-Specific Gene Expression, to Behavior

Felix Naef, Jake Yeung

Circadian rhythms in physiology and behavior evolved to resonate with daily cycles in the external environment. In mammals, organs orchestrate temporal physiology over the 24-h day, which requires extensive gene expression rhythms targeted to the right tis ...

ELSEVIER SCIENCE LONDON2018

Spatial organization of the somatosensory cortex revealed by osmFISH

Gioele La Manno

Global efforts to create a molecular census of the brain using single-cell transcriptomics are producing a large catalog of molecularly defined cell types. However, spatial information is lacking and new methods are needed to map a large number of cell typ ...

2018

Multi-layered tumor-targeting photothermal-doxorubicin releasing nanotubes eradicate tumors in vivo with negligible systemic toxicity

Paul Joseph Dyson, Zhaofu Fei, Peng Huang

Multi-layered single-walled carbon nanotubes, t ermed SWNT@BSA@Au-S-PEG -FA@DOX, which int egrate photothermal therapy with small molecule drug delivery, were prepared using a facile layer-by-layer assembly process. Oxidized and eut single-walled carbon na ...

2018

Functional composites with damage control and repair

Amaël Maximilien Cohades

Fibre Reinforced Polymer (FRP) composite structures are subjected during service to low energy impacts or unexpected loads, leading to damage. Microcracks are generally first formed in the matrix and can reach up to several hundred microns in thickness. In ...

EPFL2018

Spinning-disc confocal microscopy in the second near-infrared window (NIR-II)

Ardemis Anoush Boghossian, Benjamin Paul Johanès Gabriel Lambert, Alessandra Antonucci, Vitalijs Zubkovs

Fluorescence microscopy in the second near-infrared optical window (NIR-II, 1000–1350 nm) has become a technique of choice for non-invasive in vivo imaging. The deep penetration of NIR light in living tissue, as well as negligible tissue autofluorescence w ...

2018

Multiple roles of lymphatic vessels in peripheral lymph node development

Borja Prat Luri, Esther Bovay, Ann-Helen Willrodt

The mammalian lymphatic system consists of strategically located lymph nodes (LNs) embedded into a lymphatic vascular network. Mechanisms underlying development of this highly organized system are not fully understood. Using highresolution imaging, we show ...

2018

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