Concept

Artificial cell

Related publications (84)

Molecularly Engineered Self-Assembling Membranes for Cell-Mediated Degradation

Jeffrey Alan Hubbell, Daniela Sofia Dias Ferreira, Yi-An Lin

The use of peptide engineering to develop self-assembling membranes that are responsive to cellular enzyme activities is reported. The membranes are obtained by combining hyaluronan (HA) and a rationally designed peptide amphiphile (PA) containing a proteo ...

Wiley-Blackwell2015

Silaffins in Silica Biomineralization and Biomimetic Silica Precipitation

Carolin Christine Lechner

Biomineralization processes leading to complex solid structures of inorganic material in biological systems are constantly gaining attention in biotechnology and biomedical research. An outstanding example for biomineral morphogenesis is the formation of h ...

Mdpi Ag2015

Isolation and Characterization of Monodisperse Core Shell Nanoparticle Fractions

Francesco Stellacci, Randy Patrick Carney, Raffaele Mezzenga

Monodispersity is a key property to control the self-assembly of colloidal particles, and is typically reached after fine-tuning of the synthesis conditions. Monodisperse particle fractions can also be separated from polydisperse suspensions via ultracentr ...

American Chemical Society2015

Functional surface engineering by nucleotide-modulated potassium channel insertion into polymer membranes attached to solid supports

Henning Paul-Julius Stahlberg

Planar solid-supported membranes based on amphiphilic block copolymers represent promising systems for the artificial creation of structural surfaces. Here we introduce a method for engineering functional planar solid-supported membranes through insertion ...

Elsevier BV2014

DNA delivery with hyperbranched polylysine: A comparative study with linear and dendritic polylysine

Harm-Anton Klok, Florian Maria Wurm, David Hacker, Lucia Baldi Unser, Yashas Rajendra, Zuzana Kadlecova

PEI and polylysine are among the most investigated synthetic polymeric carriers for DNA delivery. Apart from their practical use, these 2 classes of polymers are also of interest from a fundamental point of view as they both can be prepared in different ar ...

Elsevier2013

Vesicles and Vesicle Fusion: Coarse-Grained Simulations

Julian Charles Shillcock

Biological cells are highly dynamic, and continually move material around their own volume and between their interior and exterior. Much of this transport encapsulates the material inside phospholipid vesicles that shuttle to and from, fusing with, and bud ...

Humana Press2013

An array of 100 μm × 100 μm dielectric elastomer actuators with 80% strain for tissue engineering applications

Herbert Shea, Samin Akbari

Biological cells modulate their behavior, express genes, proliferate or differentiate in response to mechanical strains ranging from 1% to 20%. There currently exists no technique to apply strain to many targeted individual cells in a larger culture in ord ...

Elsevier2012

Enhanced robustness digital holographic microscopy for demanding environment of space biology

Christian Depeursinge, Jonas Kühn, Muhammed Fatih Toy, Marcel Egli, Stéphane Richard

We describe an optimized digital holographic microscopy system (DHM) suitable for high-resolution visualization of living cells under conditions of altered macroscopic mechanical forces such as those that arise from changes in gravitational force. Experime ...

2012

Spontaneous Vesicle Self-Assembly: A Mesoscopic View of Membrane Dynamics

Amphiphilic vesicles are ubiquitous in living cells and industrially interesting as drug delivery vehicles. Vesicle self-assembly proceeds rapidly from nanometer to micrometer length scales and is too fast to image experimentally but too slow for molecular ...

American Chemical Society2012

Photocatalytic and phototoxic properties of TiO2-based nanofilaments: ESR and AFM assays

László Forró, Arnaud Magrez, Andrzej Kulik, Andrzej Sienkiewicz, Katarzyna Pierzchala

There is uncertainty in understanding of the relationship between physico-chemical parameters of nanosized titanium dioxide (nano-TiO2) and its toxicity when brought into contact with living cells. This study provides a multidisciplinary experimental insig ...

Informa Healthcare2012

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