Concept

Chorionic villi

Related publications (6)

Segmentation of Developing Human Embryo in Time-lapse Microscopy

Being able to efficiently segment a developing embryo from background clutter constitutes an important step in automated monitoring of human embryonic cells. State-of-the-art automatic segmentation methods remain ill-suited to handle the complex behavior a ...

IEEE2016

A post-processing pipeline to reconstruct the developing fetal brain using low-resolution MRI

Jean-Philippe Thiran, Meritxell Bach Cuadra, Marie Schaer

Introduction. Development of the fetal brain surface with concomitant gyrification is one of the major maturational processes of the human brain. First delineated by postmortem studies or by ultrasound, MRI has recently become a powerful tool for studying ...

2010

Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62

Johan Auwerx

Signaling cascades that control adipogenesis are essential in the regulation of body weight and obesity. The adaptor p62 controls pathways that modulate cell differentiation. We report here that p62(-/-) mice develop mature-onset obesity, leptin resistance ...

2006

PPARgamma/RXRalpha heterodimers control human trophoblast invasion

Johan Auwerx, Kristina Schoonjans

The ligand-dependent nuclear receptors PPARgamma and RXRalpha/beta were recently determined to be essential for murine placental development and trophoblast differentiation. In the current study we examined the expression and role of the PPARgamma/RXRalpha ...

2001

PPAR gamma/RXR alpha heterodimers are involved in human CG beta synthesis and human trophoblast differentiation

Johan Auwerx, Kristina Schoonjans

Recent studies performed with null mice suggested a role of either RXR alpha or PPAR gamma in murine placental development. We report here that both PPAR gamma and RXR alpha are strongly expressed in human villous cytotrophoblasts and syncytiotrophoblasts. ...

2001

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

Michel Aguet, Ajay Kumar

Double-stranded RNA-dependent protein kinase (PKR) has been implicated in interferon (IFN) induction, antiviral response and tumor suppression. We have generated mice devoid of functional PKR (Pkr%). Although the mice are physically normal and the inductio ...

1995

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