Publications related to Gliosis

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments

Graham Knott, Corrado Cali, Nicole Déglon, Tamara Zehnder, Luca Pucci, Andrea Chicca

Astrocytes orchestrate neural development by powerfully coordinating synapse formation and function and, as such, may be critically involved in the pathogenesis of neurodevelopmental abnormalities and cognitive deficits commonly observed in psychiatric dis ...

2020

Lactate enhancing compounds and uses thereof

Pierre Magistretti, Sylvain Eric Lengacher, Charles Léonard Finsterwald

Abstract of the invention: The present invention relates to new agents useful for stimulating release of lactate by astrocytes. The invention further relates to methods of preparation, formulations and therapeutic uses of those agents, notably for the prev ...

2020

Serum GFAP in multiple sclerosis: correlation with disease type and MRI markers of disease severity

Tobias Kober, Bénédicte Marie Maréchal, Mario Joao Fartaria de Oliveira

Neurofilament light chain (NfL) has been demonstrated to correlate with multiple sclerosis disease severity as well as treatment response. Nevertheless, additional serum biomarkers are still needed to better differentiate disease activity from disease prog ...

2020

Optical phase contrast imaging of human retinal cells by changing the tissue refractive index

Christophe Moser, Timothé Laforest, Laura Emmanuelle Kowalczuk, Mathieu Künzi

Purpose : Based on oblique partially coherent illumination of transparent samples, we developed a simple custom Optical Phase Imaging (OPI) microscope providing a label-free, semi-quantitative phase contrast imaging. The aim of this study was to explore th ...

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2020

Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology

Bernard Schneider, Philippe Colin, Vanessa Laversenne

The brain pathology of Alzheimer’s disease (AD) is characterized by the misfolding and aggregation of both the amyloid beta (Aβ) peptide and hyperphosphorylated forms of the tau protein. Initial Aβ deposition is considered to trigger a sequence of deleteri ...

2020

Extra-axonal restricted diffusion as an in-vivo marker of reactive microglia

Anne des Rieux, Gaëtan Olivier D Rensonnet, Benoît Macq

Reactive microgliosis is an important pathological component of neuroinflammation and has been implicated in a wide range of brain diseases including brain tumors, multiple sclerosis, Parkinson's disease, Alzheimer's disease, and schizophrenia. Mapping rea ...

2019

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

Cristina Ramona Cudalbu, Jocelin Grosse, Katarzyna Pierzchala, Veronika Rackayová

Background & Aims: The sequence of events in hepatic encephalopathy (HE) remains unclear. Using the advantages of in vivo 1H-MRS (9.4T) we aimed to analyse the time-course of disease in an established model of type C HE by analysing the longitudinal change ...

2019

Ultra high magnetic field for glial contribution into brain metabolism studied by MR spectroscopy and CEST methods for molecular imaging of glycogen

Elise Marie Catherine Vinckenbosch

Magnetic resonance at ultra-high field increases signal and spectral dispersion. In this thesis, I use those characteristics to investigate three different subjects in 13C spectroscopy, hyperpolarized methods and chemical exchange saturation transfer (CEST ...

EPFL2018

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Gliosis

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments

Lactate enhancing compounds and uses thereof

Impairment of Glycolysis-Derived L-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease

Serum GFAP in multiple sclerosis: correlation with disease type and MRI markers of disease severity

Optical phase contrast imaging of human retinal cells by changing the tissue refractive index

Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology

Extra-axonal restricted diffusion as an in-vivo marker of reactive microglia

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

Application of anti-amyloid beta immunization using encapsulated cell technology in mouse models of Alzheimer's disease

Ultra high magnetic field for glial contribution into brain metabolism studied by MR spectroscopy and CEST methods for molecular imaging of glycogen

Graph Chatbot

Chat with Graph Search

Anti-Aβ antibodies bound to neuritic plaques enhance microglia activity and mitigate tau pathology

Extra-axonal restricted diffusion as an in-vivo marker of reactive microglia

Longitudinal neurometabolic changes in the hippocampus of a rat model of chronic hepatic encephalopathy

Lactate enhancing compounds and uses thereof

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments

Impairment of Glycolysis-Derived L-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease

Serum GFAP in multiple sclerosis: correlation with disease type and MRI markers of disease severity

Optical phase contrast imaging of human retinal cells by changing the tissue refractive index

Application of anti-amyloid beta immunization using encapsulated cell technology in mouse models of Alzheimer's disease

Ultra high magnetic field for glial contribution into brain metabolism studied by MR spectroscopy and CEST methods for molecular imaging of glycogen