Concept

Retina

Related publications (257)

Overcoming the resolution limit in retinal imaging using the scattering properties of the sclera

Demetri Psaltis, Christophe Moser, Timothé Laforest, Dino Carpentras

In-vivo imaging of the eye's fundus is widely used to study eye's health. State of the art Adaptive Optics devices can resolve features up to a lateral resolution of 1.5 um. This resolution is still above what is needed to observe subcellular structures su ...

Spie-Int Soc Optical Engineering2016

Retinotopic encoding of the Ternus-Pikler display reflected in the early visual areas

Michael Herzog, Wietske Van der Zwaag, Gijs Plomp, Yvonne Evelina Thunell

The visual representation of the world is often assumed to be retinotopic, and many visual brain areas are indeed organized retinotopically. Visual perception, however, is not based on a reference frame anchored in retinotopic coordinates. For example, whe ...

Association for Research in Vision and Ophthalmology (ARVO)2016

Reducing acquisition time for axon diameter mapping using global optimization in the spatial-angular-microstructure space

Jean-Philippe Thiran, Yves Wiaux, Erick Jorge Canales Rodriguez, David Paul Roger Romascano, Alessandro Daducci, Anna Auria Rasclosa, Tim Bjørn Dyrby

State-of-the-art microstructure imaging methods usually fit biophysical models to the diffusion MRI data on a voxel-by-voxel basis using non-linear procedures that require both long acquisitions and processing time. We recently introduced AMICO, a framewor ...

2016

Tgfbi/Bigh3 silencing activates ERK in mouse retina

BIGH3 is a secreted protein, part of the extracellular matrix where it interacts with collagen and integrins on the cell surface. BIGH3 can play opposing roles in cancer, acting as either tumor suppressor or promoter, and its mutations lead to different fo ...

Academic Press Ltd- Elsevier Science Ltd2015

Retinal prostheses: progress toward the next generation implants

Diego Ghezzi

In the last decade, various clinical trials proved the capability of visual prostheses, in particular retinal implants, to restore a useful form of vision. These encouraging results promoted the emerging of several strategies for neuronal stimulation aimin ...

Frontiers Research Foundation2015

Coating nanocarriers with hyaluronic acid facilitates intravitreal drug delivery for retinal gene therapy

Hendrik Georges Deschout

Retinal gene therapy could potentially affect the lives of millions of people suffering from blinding disorders. Yet, one of the major hurdles remains the delivery of therapeutic nucleic acids to the retinal target cells. Due to the different barriers that ...

Elsevier2015

A unified framework for evaluating non-visual spectral effectiveness of ocular light exposure: key concepts

Marilyne Andersen, María Lovísa Ámundadóttir, Steven W. Lockley

The first evidence for a novel type of photoreceptor in humans was published in the form of an action spectrum for melatonin suppression. This action spectrum has very different spectral sensitivities compared to rod and cone photoreceptors. This discovery ...

2015

Gene therapy and bioengineering for retinal diseases: what is the future?

Diego Ghezzi

Sight restoration after retinal degeneration still represents an unmet goal. Since therapeutic strategies increasingly require interdisciplinary competencies, photoreceptor degeneration is attracting several research areas, including: life science, materia ...

2015

Abrogation of HMX1 Function Causes Rare Oculoauricular Syndrome Associated With Congenital Cataract, Anterior Segment Dysgenesis, and Retinal Dystrophy

PURPOSE. To define the phenotypic manifestation, confirm the genetic basis, and delineate the pathogenic mechanisms underlying an oculoauricular syndrome (OAS). METHODS. Two individuals from a consanguineous family underwent comprehensive clinical phenotyp ...

Assoc Research Vision Ophthalmology Inc2015

Elucidating the role of Hmx1 during mouse development

Linda Bapst

This thesis focuses on the study of H6 homeobox 1 (HMX1) gene, a homeobox-containing transcription factor involved in sensory organ and eye development and responsible for the oculo-auricular syndrome of Schorderet-Munier-Franceschetti. The purpose of my s ...

EPFL2015

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