Inhalation (or inspiration) happens when air or other gases enter the lungs.
Inhalation of air, as part of the cycle of breathing, is a vital process for all human life. The process is autonomic (though there are exceptions in some disease states) and does not need conscious control or effort. However, breathing can be consciously controlled or interrupted (within limits).
Breathing allows oxygen (which humans and a lot of other species need for survival) to enter the lungs, from where it can be absorbed into the bloodstream.
Examples of accidental inhalation includes inhalation of water (e.g. in drowning), smoke, food, vomitus and less common foreign substances (e.g. tooth fragments, coins, batteries, small toy parts, needles).
Legal – helium, nitrous oxide ("laughing gas")
Illegal – various gaseous, vaporised or aerosolized recreational drugs
Various specialized investigations use the inhalation of known substances for diagnostic purposes. Examples include pulmonary function testing (e.g. nitrogen washout test, diffusion capacity testing (carbon monoxide, helium, methane)) and diagnostic radiology (e.g. radioactive xenon isotopes).
Gases and other drugs used in anaesthesia include oxygen, nitrous oxide, helium, xenon, volatile anaesthetic agents. Medication for asthma, croup, cystic fibrosis and some other conditions.
Inhalation begins with the contraction of the muscles attached to the rib cage; this causes an expansion in the chest cavity. Then takes place the onset of contraction of the thoracic diaphragm, which results in expansion of the intrapleural space and an increase in negative pressure according to Boyle's law. This negative pressure generates airflow because of the pressure difference between the atmosphere and alveolus.
The inflow of air into the lungs occurs via the respiratory airways. In health, these airways begin with the nose. It is possible to begin with the mouth, which is the backup breathing system. However, chronic mouth breathing leads to, or is a sign of, illness.