Concept
Mantoux test
Related publications (32)
Single-cell analysis of the interactions between Mycobacterium tuberculosis and macrophages
Mycobacterium Tuberculosis is a highly effective pathogen infecting nearly a third of the world's population. An M. tuberculosis infection starts when droplets containing bacteria enter an individual's lungs. The first host cells to contact the bacteria ar ...
EPFL2024Molecular gas in CLASH brightest cluster galaxies at z similar to 0.2-0.9
Pascale Jablonka, Gianluca Castignani
Brightest cluster galaxies (BCGs) are excellent laboratories for the study of galaxy evolution in dense Mpc-scale environments. We used the IRAM-30 m to observe, in CO(1 -> 0), CO(2 -> 1), CO(3 -> 2), or CO(4 -> 3), 18 BCGs at z similar to 0.2-0.9 drawn fr ...
EDP SCIENCES S A2020Environmental processing in cluster core galaxies at z=1.7
Today, the brightest cluster galaxies (BCGs) are passive and very massive galaxies at the center of their clusters, and they still accrete mass through swallowing companions and gas from cooling flows. However their formation history is not well known. We ...
2020Soft Hydrogel Zwitterionic Coatings Minimize Fibroblast and Macrophage Adhesion on Polyimide Substrates
Silvestro Micera, Anna Zahoranova, igor lacik
Minimizing the foreign body reaction to polyimide-based implanted devices plays a pivotal role in several biomedical applications. In this work, we propose materials exhibiting nonbiofouling properties and a Young's modulus reflecting that of soft human ti ...
AMER CHEMICAL SOC2019New 1-hydroxy-2-thiopyridine derivatives active against both replicating and dormant Mycobacterium tuberculosis
Tuberculosis (TB) treatment is confounded by the range of metabolic states displayed by Mycobacterium tuberculosis, by the long duration required and by the increasing prevalence of drug-resistant strains. Latent TB infection is especially difficult to tre ...
Elsevier Science Bv2017Genomic and transcriptomic analysis of the streptomycin-dependent Mycobacterium tuberculosis strain 18b
Stewart Cole, Claudia Sala, Andrej Benjak, Ming Zhang, Jérémie Piton, Swapna Uplekar
Background: The ability of Mycobacterium tuberculosis to establish a latent infection (LTBI) in humans confounds the treatment of tuberculosis. Consequently, there is a need to discover new therapeutic agents that can kill M. tuberculosis both during activ ...
BioMed Central2016Investigation of 2R-Cell Degradation under Thermal Cycling and RedOx Cycling Conditions by Electrochemical Impedance Spectroscopy
Jan Van Herle, Stefan Diethelm, Vaibhav Singh
A 2R-cell with a 10 cm2 active area LSCF cathode on a CGO buffer layer was tested at 780°C under thermal and RedOx cycling conditions; 20 thermal cycles were performed between 780°C and 100°C, using 200°C/h heating ramps and natural cooling, followed by 20 ...
2015Survival of Free and Encapsulated Human and Rat Islet Xenografts Transplanted into the Mouse Bone Marrow
Jutta Christine Wandrey, Redouan Mahou, Yannick Müller
Bone marrow was recently proposed as an alternative and potentially immune-privileged site for pancreatic islet transplantation. The aim of the present study was to assess the survival and rejection mechanisms of free and encapsulated xenogeneic islets tra ...
Public Library of Science2014In Vitro and In Vivo Activities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis
Stewart Cole, Neeraj Dhar, Claudia Sala, Anthony Vocat, Ming Zhang
Oxazolidinones represent a new class of antituberculosis drugs that exert their function by inhibiting protein synthesis. Here, we compared the activities of three oxazolidinones, linezolid, PNU-100480, and AZD5847, against latent tuberculosis using a simp ...
Amer Soc Microbiology2014Measured and Modeled Toxicokinetics in Cultured Fish Cells and Application to In Vitro - In Vivo Toxicity Extrapolation
Kristin Schirmer, Julita Maria Stadnicka-Michalak
Effect concentrations in the toxicity assessment of chemicals with fish and fish cells are generally based on external exposure concentrations. External concentrations as dose metrics, may, however, hamper interpretation and extrapolation of toxicological ...
Public Library Science2014