Explores cellular senescence mechanisms induced by mitogenic signals, DNA damage, and oncogenes, emphasizing the role of key regulatory proteins and the impact on cell division.
Examines how a receptor regulates proteostasis in C. elegans, emphasizing the importance of maintaining cellular function and preventing protein misfolding diseases.
Explores drug targets, particularly nuclear receptors like PPARy and pregnane X receptor, and their impact on endocrine signaling and drug pharmacokinetics.