Publications related to Pyramidal cell

Directional sensitivity of cortical neurons towards TMS induced electric fields

Werner Alfons Hilda Van Geit, Aurélien Tristan Jaquier

We derived computationally efficient average response models of different types of cortical neurons, which are subject to external electric fields from Transcranial Magnetic Stimulation. We used 24 reconstructions of pyramidal cells (PC) from layer 2/3, 24 ...

2023

Controlling morpho-electrophysiological variability of neurons with detailed biophysical models

Henry Markram, Lida Kanari, Werner Alfons Hilda Van Geit, Alexis Arnaudon, Maria Reva, Mickael Maurice Zbili

Variability is a universal feature among biological units such as neuronal cells as they enable a robust encoding of a high volume of information in neuronal circuits and prevent hyper synchronizations such as epileptic seizures. While most computational s ...

2023

Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex

Werner Alfons Hilda Van Geit, Anatoly Buchin

The brain consists of many cell classes yet in vivo electrophysiology recordings are typically unable to identify and monitor their activity in the behaving animal. Here, we employed a systematic approach to link cellular, multi-modal in vitro properties f ...

2023

A subpopulation of cortical VIP-expressing interneurons with highly dynamic spines

Graham Knott, Jérôme Blanc, Christina Georgiou, Kok Sin Lee

Structural synaptic plasticity may underlie experience and learning-dependent changes in cortical circuits. In contrast to excitatory pyramidal neurons, insight into the structural plasticity of inhibitory neurons remains limited. Interneurons are divided ...

NATURE PORTFOLIO2022

The Neuron Phenotype Ontology: A FAIR Approach to Proposing and Classifying Neuronal Types

Sean Lewis Hill, Mohameth François Sy

The challenge of defining and cataloging the building blocks of the brain requires a standardized approach to naming neurons and organizing knowledge about their properties. The US Brain Initiative Cell Census Network, Human Cell Atlas, Blue Brain Project, ...

HUMANA PRESS INC2022

Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types

Werner Alfons Hilda Van Geit, Anatoly Buchin

Which cell types constitute brain circuits is a fundamental question, but establishing the correspondence across cellular data modalities is challenging. Bio-realistic models allow probing cause-and-effect and linking seemingly disparate modalities. Here, ...

2022

Does powder averaging remove dispersion bias in diffusion MRI diameter estimates within real 3D axonal architectures?

Marco Pizzolato, Tim Bjørn Dyrby

Noninvasive estimation of axon diameter with diffusion MRI holds the potential to investigate the dynamic properties of the brain network and pathology of neurodegenerative diseases. Recent studies use powder averaging to account for complex white matter a ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

High synaptic threshold for dendritic NMDA spike generation in human layer 2/3 pyramidal neurons

James Gonzalo King, Suraj Honnuraiah

Neurons receive synaptic input primarily onto their dendrites. While we know much about the electrical properties of dendrites in rodents, we have only just started to describe their properties in the human brain. Here, we investigate the capacity of human ...

2022

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Pyramidal cell

Loss of Motor Cortical Inputs to the Red Nucleus after CNS Disorders in Nonhuman Primates

Directional sensitivity of cortical neurons towards TMS induced electric fields

Controlling morpho-electrophysiological variability of neurons with detailed biophysical models

Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex

A subpopulation of cortical VIP-expressing interneurons with highly dynamic spines

Different priming states of synaptic vesicles underlie distinct release probabilities at hippocampal excitatory synapses

The Neuron Phenotype Ontology: A FAIR Approach to Proposing and Classifying Neuronal Types

Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types

Does powder averaging remove dispersion bias in diffusion MRI diameter estimates within real 3D axonal architectures?

High synaptic threshold for dendritic NMDA spike generation in human layer 2/3 pyramidal neurons

Graph Chatbot

Chat with Graph Search

Loss of Motor Cortical Inputs to the Red Nucleus after CNS Disorders in Nonhuman Primates

Directional sensitivity of cortical neurons towards TMS induced electric fields

The Neuron Phenotype Ontology: A FAIR Approach to Proposing and Classifying Neuronal Types

Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types

Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex

High synaptic threshold for dendritic NMDA spike generation in human layer 2/3 pyramidal neurons

Controlling morpho-electrophysiological variability of neurons with detailed biophysical models

Does powder averaging remove dispersion bias in diffusion MRI diameter estimates within real 3D axonal architectures?

Different priming states of synaptic vesicles underlie distinct release probabilities at hippocampal excitatory synapses

A subpopulation of cortical VIP-expressing interneurons with highly dynamic spines