Publications associées à Cellule pyramidale

Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex

Werner Alfons Hilda Van Geit, Anatoly Buchin

The brain consists of many cell classes yet in vivo electrophysiology recordings are typically unable to identify and monitor their activity in the behaving animal. Here, we employed a systematic approach to link cellular, multi-modal in vitro properties f ...

2023

A subpopulation of cortical VIP-expressing interneurons with highly dynamic spines

Graham Knott, Jérôme Blanc, Christina Georgiou, Kok Sin Lee

Structural synaptic plasticity may underlie experience and learning-dependent changes in cortical circuits. In contrast to excitatory pyramidal neurons, insight into the structural plasticity of inhibitory neurons remains limited. Interneurons are divided ...

NATURE PORTFOLIO2022

The Neuron Phenotype Ontology: A FAIR Approach to Proposing and Classifying Neuronal Types

Sean Lewis Hill, Mohameth François Sy

The challenge of defining and cataloging the building blocks of the brain requires a standardized approach to naming neurons and organizing knowledge about their properties. The US Brain Initiative Cell Census Network, Human Cell Atlas, Blue Brain Project, ...

HUMANA PRESS INC2022

Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types

Werner Alfons Hilda Van Geit, Anatoly Buchin

Which cell types constitute brain circuits is a fundamental question, but establishing the correspondence across cellular data modalities is challenging. Bio-realistic models allow probing cause-and-effect and linking seemingly disparate modalities. Here, ...

2022

High synaptic threshold for dendritic NMDA spike generation in human layer 2/3 pyramidal neurons

James Gonzalo King, Suraj Honnuraiah

Neurons receive synaptic input primarily onto their dendrites. While we know much about the electrical properties of dendrites in rodents, we have only just started to describe their properties in the human brain. Here, we investigate the capacity of human ...

2022

Long term effects of peripubertal stress on excitatory and inhibitory circuits in the prefrontal cortex of male and female mice

Maria del Carmen Sandi Perez

The impact of stressful events is especially important during early life, because certain cortical regions, especially the prefrontal cortex (PFC), are still developing. Consequently, aversive experiences that occur during the peripubertal period can cause ...

ELSEVIER SCIENCE INC2021

HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data

Eilif Benjamin Muller, Werner Alfons Hilda Van Geit, Armando Romani, Szabolcs Kali, Carmen Alina Lupascu, Rosanna Migliore, Luca Leonardo Bologna, Sàra Sàray, Shailesh Appukuttan

Anatomically and biophysically detailed data-driven neuronal models have become widely used tools for understanding and predicting the behavior and function of neurons. Due to the increasing availability of experimental data from anatomical and electrophys ...

PUBLIC LIBRARY SCIENCE2021

Quantum Sensing of Free Radicals in Primary Human Dendritic Cells

Mayeul Sylvain Chipaux

Free radicals are crucial indicators for stress and appear in all kinds of pathogenic conditions, including cancer, cardiovascular diseases, and infection. However, they are difficult to detect due to their reactivity and low abundance. We use relaxometry ...

AMER CHEMICAL SOC2021

The Role of Hub Neurons in Modulating Cortical Dynamics

Henry Markram, Oren Amsalem, Idan Segev, Eyal Gal, Michael London

Many neurodegenerative diseases are associated with the death of specific neuron types in particular brain regions. What makes the death of specific neuron types particularly harmful for the integrity and dynamics of the respective network is not well unde ...

2021

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Cellule pyramidale

Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex

A subpopulation of cortical VIP-expressing interneurons with highly dynamic spines

Different priming states of synaptic vesicles underlie distinct release probabilities at hippocampal excitatory synapses

The Neuron Phenotype Ontology: A FAIR Approach to Proposing and Classifying Neuronal Types

Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types

High synaptic threshold for dendritic NMDA spike generation in human layer 2/3 pyramidal neurons

Long term effects of peripubertal stress on excitatory and inhibitory circuits in the prefrontal cortex of male and female mice

HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data

Quantum Sensing of Free Radicals in Primary Human Dendritic Cells

The Role of Hub Neurons in Modulating Cortical Dynamics

Graph Chatbot

Chattez avec Graph Search

Different priming states of synaptic vesicles underlie distinct release probabilities at hippocampal excitatory synapses

The Neuron Phenotype Ontology: A FAIR Approach to Proposing and Classifying Neuronal Types

Single-neuron models linking electrophysiology, morphology, and transcriptomics across cortical cell types

High synaptic threshold for dendritic NMDA spike generation in human layer 2/3 pyramidal neurons

Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex

Long term effects of peripubertal stress on excitatory and inhibitory circuits in the prefrontal cortex of male and female mice

Quantum Sensing of Free Radicals in Primary Human Dendritic Cells

The Role of Hub Neurons in Modulating Cortical Dynamics

A subpopulation of cortical VIP-expressing interneurons with highly dynamic spines

HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data