Concept

Gestational diabetes

Related publications (99)

Unaltered cocaine self-administration in the prenatal LPS rat model of schizophrenia

Although cocaine abuse is up to three times more frequent among schizophrenic patients, it remains unclear why this should be the case and whether sex influences this relationship. Using a maternal immune activation model of schizophrenia, we tested whethe ...

Pergamon-Elsevier Science Ltd2016

Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging

Theo Lasser, Anne Grapin-Botton, Martin Villiger, Arno Pino Bouwens, Daniel Pawel Szlag, Corinne Berclaz, Jérôme Extermann, Joan Goulley

Aims/hypothesis It is generally accepted that structural and functional quantitative imaging of individual islets would be beneficial to elucidate the pathogenesis of type 1 diabetes. We here introduce functional optical coherence imaging (FOCI) for fast, ...

Springer Verlag2016

System for Adjusting Pressure Locally Acting on the Skin and Subcutaneous Tissue

Yves Perriard, Yoan René Cyrille Civet, Daniel Grivon

The invention relates to a system for adjusting pressure locally acting on the skin. Said system includes a set of adjacent modules distributed so as to form a layer. Each module includes a cushion capable of changing shape and comprising a cavity, a valve ...

Organisation Mondiale de la Proprieté Intellectuelle2016

Evidence for a Direct Effect of the NAD(+) Precursor Acipimox on Muscle Mitochondrial Function in Humans

Johan Auwerx, Evan Graehl Williams, Norman Lionel Moullan, Eija Riitta Pirinen

Recent preclinical studies showed the potential of nicotinamide adenine dinucleotide (NAD(+)) precursors to increase oxidative phosphorylation and improve metabolic health, but human data are lacking. We hypothesize that the nicotinic acid derivative acipi ...

American Diabetes Association2015

A Therapy Parameter-based Model for Predicting Blood Glucose Concentrations in Patients with Type 1 Diabetes

Denis Gillet, Grégory François, Alain Bock

In this paper, the problem of predicting blood glucose concentrations (BG) for the treatment of patients with type 1 diabetes, is addressed. Predicting BG is of very high importance as most treatments, which consist in exogenous insulin injections, rely on ...

Elsevier2015

Combined Optical Coherence and Fluorescence Microscopy to assess dynamics and specificity of pancreatic beta-cell tracers

Theo Lasser, Christophe Pache, Anne Grapin-Botton, Arno Pino Bouwens, Daniel Pawel Szlag, Corinne Berclaz, Antonio Lopez

The identification of a beta-cell tracer is a major quest in diabetes research. However, since MRI, PET and SPECT cannot resolve individual islets, optical techniques are required to assess the specificity of these tracers. We propose to combine Optical Co ...

2015

Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis

Daniel Constam, Jacques Rougemont, Anne Grapin-Botton, Joan Goulley, Laurence Anne E Lemaire, Yung Hae Kim

In human, mutations in bicaudal C1 (BICC1), an RNA binding protein, have been identified in patients with kidney dysplasia. Deletion of Bicc1 in mouse leads to left-right asymmetry randomization and renal cysts. Here, we show that BICC1 is also expressed i ...

Company Of Biologists Ltd2015

REST represses a subset of the pancreatic endocrine differentiation program

Anne Grapin-Botton, Yung Hae Kim

To contribute to devise successful beta-cell differentiation strategies for the cure of Type 1 diabetes we sought to uncover barriers that restrict endocrine fate acquisition by studying the role of the transcriptional repressor REST in the developing panc ...

Academic Press Inc Elsevier Science2015

Definition and quantification of acute inflammatory white matter injury in the immature brain by MRI/MRS at high magnetic field

Rolf Gruetter, Nicolas Kunz

Background: Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. The impact of maternal supplementat ...

Nature Publishing Group2014

Protective effects of maternal nutritional supplementation with lactoferrin on growth and brain metabolism

Rolf Gruetter, Yohan Van de Looij, Sylviane Métairon

Background:Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. The impact of maternal supplementati ...

Nature Publishing Group2014

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