Concept
Adult neurogenesis
Related publications (165)
Principles of Network Plasticity in Neocortical Microcircuits
Synaptic plasticity underlies our ability to learn and adapt to the constantly changing environment. The phenomenon of synapses changing their efficacy in an activity-dependent manner is often studied in small groups of neurons in vitro or indirectly throu ...
EPFL2023Targeted regeneration of spinal cord neurons across a complete injury restores walking
Spinal cord injury (SCI) interrupts axonal connections between the brain and the spinal cord, and is characterized by a spectrum of sensorimotor and autonomic impairments. While spontaneous recovery is limited, recent studies have shown that functional imp ...
EPFL2023A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes
Kathryn Hess Bellwald, Lida Kanari, Martina Scolamiero
Environmental cues influence the highly dynamic morphology of microglia. Strategies to characterize these changes usually involve user-selected morphometric features, which preclude the identification of a spectrum of context-dependent morphological phenot ...
NATURE PORTFOLIO2022Incomplete Recovery of Zebrafish Retina Following Cryoinjury
Zebrafish show an extraordinary potential for regeneration in several organs from fins to central nervous system. Most impressively, the outcome of an injury results in a near perfect regeneration and a full functional recovery. Indeed, among the various i ...
MDPI2022A functional model of adult dentate gyrus neurogenesis
Wulfram Gerstner, Olivia Gozel
In adult dentate gyrus neurogenesis, the link between maturation of newborn neurons and their function, such as behavioral pattern separation, has remained puzzling. By analyzing a theoretical model, we show that the switch from excitation to inhibition of ...
2021HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data
Eilif Benjamin Muller, Werner Alfons Hilda Van Geit, Armando Romani, Szabolcs Kali, Carmen Alina Lupascu, Rosanna Migliore, Luca Leonardo Bologna, Sàra Sàray, Shailesh Appukuttan
Anatomically and biophysically detailed data-driven neuronal models have become widely used tools for understanding and predicting the behavior and function of neurons. Due to the increasing availability of experimental data from anatomical and electrophys ...
PUBLIC LIBRARY SCIENCE2021Optogenetic Interrogation of Circuits Following Neurotrauma
Grégoire Courtine, Steven Lee Ceto
Biological and engineering strategies for neural repair and recovery from neurotrauma continue to emerge at a rapid pace. Until recently, studies of the impact of neurotrauma and repair strategies on the reorganization of the central nervous system have fo ...
FRONTIERS MEDIA SA2021