Carbohydrate chemistry is a subdiscipline of chemistry primarily concerned with the detection, synthesis, structure, and function of carbohydrates. Due to the general structure of carbohydrates, their synthesis is often preoccupied with the selective formation of glycosidic linkages and the selective reaction of hydroxyl groups; as a result, it relies heavily on the use of protecting groups.
monosaccharides
Individual saccharide residues are termed monosaccharides.
Carbohydrate synthesis
Carbohydrate synthesis is a sub-field of organic chemistry concerned specifically with the generation of natural and unnatural carbohydrate structures. This can include the synthesis of monosaccharide residues or structures containing more than one monosaccharide, known as oligosaccharides.
Chemical glycosylation
Fischer glycosidation
Glycosyl halide
Koenigs-Knorr reaction
Carbohydrate acetalisation
Trimethylsilyl
Benzyl Ether
para-methoxybenzyl ether
Oligosaccharide
Carbohydrates are reactants in many organic reactions. For example:
Cyanohydrin reaction
Lobry-de Bruyn-van Ekenstein transformation
Amadori rearrangement
Nef reaction
Wohl degradation
Tipson-Cohen reaction
Ferrier rearrangement
Ferrier II reaction
Carbohydrates have four major functions within the body:
Energy supply, particularly for the brain in the form of glucose
Avoiding the breakdown of amino acids for energy
Avoiding ketosis from the breakdown of fatty acids
Cellular and protein recognition
Carbohydrate catabolism and Glucose
Amino acid catabolism
Ketosis
GlycoproteinMajor histocompatibility complexABO blood group system and Antibody
Glycoprotein hormones may be removed by the liver from the bloodstream when the passage of time causes the breaking-off of carbohydrates from the glycoproteins.
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Glycosyltransferases (GTFs, Gtfs) are enzymes (EC 2.4) that establish natural glycosidic linkages. They catalyze the transfer of saccharide moieties from an activated nucleotide sugar (also known as the "glycosyl donor") to a nucleophilic glycosyl acceptor molecule, the nucleophile of which can be oxygen- carbon-, nitrogen-, or sulfur-based. The result of glycosyl transfer can be a carbohydrate, glycoside, oligosaccharide, or a polysaccharide. Some glycosyltransferases catalyse transfer to inorganic phosphate or water.
In chemistry, a glycoside ˈɡlaɪkəsaɪd is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. Several species of Heliconius butterfly are capable of incorporating these plant compounds as a form of chemical defense against predators.
A glycosidic bond or glycosidic linkage is a type of ether bond that joins a carbohydrate (sugar) molecule to another group, which may or may not be another carbohydrate. A glycosidic bond is formed between the hemiacetal or hemiketal group of a saccharide (or a molecule derived from a saccharide) and the hydroxyl group of some compound such as an alcohol. A substance containing a glycosidic bond is a glycoside.