Concept

Tandem mass spectrometry

Related publications (558)

Cross-code gyrokinetic verification and benchmark on the linear collisionless dynamics of the geodesic acoustic mode

The linear properties of the geodesic acoustic modes (GAMs) in tokamaks are investigated by means of the comparison of analytical theory and gyrokinetic numerical simulations. The dependence on the value of the safety factor, finite-orbit-width of the ions ...

Amer Inst Physics2017

Device and Method for Ion Cyclotron Resonance Mass Spectrometry

Yury Tsybin, Anton Kozhinov, Konstantin Nagornov

The present invention relates to a method and device for measuring m/z ratios of ions in ion cyclotron resonance (ICR) mass spectrometry. The described ion traps for ICR mass spectrometry are distinct from the previous configurations by having one or many ...

2017

Cryogenic Ion Spectroscopy of Peptides and Glycans

Chiara Masellis

Understanding the structure of biomolecules, which are directly related to physiological processes that take place in the human body, has always generated a large interest in the scientific community. In this thesis we focus our attention on two of these c ...

EPFL2017

Glycosaminoglycan Analysis by Cryogenic Messenger-Tagging IR Spectroscopy Combined with IMS-MS

Thomas Rizzo, Michael Zachary Kamrath, Chiara Masellis, Neelam Khanal

We combine ion mobility spectrometry with cryogenic, messenger-tagging, infrared spectroscopy and mass spectrometry to . identify different isomeric disaccharides of chondroitin sulfate (CS) and heparan sulfate (HS), which are representatives of two major ...

2017

Cryogenic Vibrational Spectroscopy Provides Unique Fingerprints for Glycan Identification

Thomas Rizzo, Michael Zachary Kamrath, Chiara Masellis, Neelam Khanal

The structural characterization of glycans by mass spectrometry is particularly challenging. This is because of the high degree of isomerism in which glycans of the same mass can differ in their stereochemistry, attachment points, and degree of branching. ...

2017

Electrostatic spray ionization from 384-well microtiter plates for mass spectrometry analysis based enzyme assay and drug metabolism screening

Hubert Girault, Liang Qiao, Tzu-En Lin, Elena Tobolkina, Xiaoqin Zhong, Yan Deng, Emna Belghith

We have realized the direct ionization of samples from wells of microtiter plates under atmospheric conditions for mass spectrometry analysis without any liquid delivery system or any additional interface. The microtiter plate is a commercially available 3 ...

American Chemical Society2017

New ionization and tagging methods for mass spectrometry

Xiaoqin Zhong

Mass spectrometry (MS) is an essential detection tool in bioanalytical chemistry owing to its exceptional selectivity and sensitivity, paired with rapid analyte identification and quantification. In this thesis, two classical MS and a newly developed ioniz ...

EPFL2017

Extremely Slow Spontaneous Electron Trapping in Photodoped n-Type CdSe Nanocrystals

Arianna Marchioro

The trapping dynamics of conduction-band electrons in colloidal degenerately doped n-CdSe nanocrystals prepared by photochemical reduction (photodoping) were measured by direct optical methods. The nanocrystals show spontaneous electron trapping with distr ...

2017

Improving spatial and spectral resolution of TCV Thomson scattering

Basil Duval, Patrick Blanchard, René Chavan, Joan Decker, Xavier Llobet, Yanis Andrebe, Matthieu Toussaint, Pierre Lavanchy, Philippe Marmillod, Robert Bertizzolo

The recently completed MST2 upgrade to the Thomson scattering (TS) system on TCV (Tokamak a Configuration Variable) at the Swiss Plasma Center aims to provide an enhanced spatial and spectral resolution while maintaining the high level of diagnostic flexib ...

Iop Publishing Ltd2017

Identification of Chlamydomonas Central Core Centriolar Proteins Reveals a Role for Human WDR90 in Ciliogenesis

Pierre Gönczy, Romain Hamelin, Florence Armand, Coralie Busso, Paul Guichard, Virginie Hamel, Isabelle Fluckiger

Centrioles are evolutionarily conserved macromolecular structures that are fundamental to form cilia, flagella, and centrosomes. Centrioles are 9-fold symmetrical microtubule-based cylindrical barrels comprising three regions that can be clearly distinguis ...

2017

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