Publications related to Atheroma

Spatial analysis of 10-year predicted risk and incident atherosclerotic cardiovascular disease: the CoLaus cohort

Stéphane Joost, Idris Guessous, David Nicolas De Ridder, Guillaume Jordan

Whether cardiovascular risk scores geographically aggregate and inform on spatial development of atherosclerotic cardiovascular diseases (ASCVD) remains unknown. Our aim is to determine the spatial distribution of 10-year predicted cardiovascular risk and ...

2024

Combining European and US risk prediction models with polygenic risk scores to refine cardiovascular prevention: the CoLaus|PsyCoLaus Study

Jacques Fellay, Christian Axel Wandall Thorball, Stéphane Fournier, Roxane De La Harpe

Lay Summary The aim of this study is to determine whether using polygenic risk scores improves the prediction of atherosclerotic cardiovascular disease risk when combined with clinical scores currently recommended by European and US guidelines on cardiovas ...

OXFORD UNIV PRESS2023

Impact and implications of mixed plaque class in automated characterization of complex atherosclerotic lesions

Yanan Niu

Atherosclerosis is a complex disease altering vasculature morphology, and subsequently flow, with progressive plaque formation, mural disruption, and lumen occlusion. Determination of clinically-relevant plaque components-particularly calcium, lipid, and f ...

PERGAMON-ELSEVIER SCIENCE LTD2022

Sub-micrometer morphology of human atherosclerotic plaque revealed by synchrotron radiation-based mu CT-A comparison with histology

Goran Lovric, Anne Bonnin

Histology is a long standing and well-established gold standard for pathological characterizations. In recent years however, synchrotron radiation-based micro-computed tomography (SR mu CT) has become a tool for extending the imaging of two-dimensional thi ...

PUBLIC LIBRARY SCIENCE2022

Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons Living With HIV: The Swiss HIV Cohort Study

Jacques Fellay, Christian Axel Wandall Thorball

Background. In people living with human immunodeficiency virus (HIV) (PLWH), individual polygenic risk scores (PRSs) are associated with coronary artery disease (CAD) events. Whether PRSs are associated with subclinical CAD is unknown. Methods. In Swiss HI ...

OXFORD UNIV PRESS INC2022

Considerations for analysis of endothelial shear stress and strain in FSI models of atherosclerosis

Lydia Aslanidou, Fotios Savvopoulos

Atherosclerosis is a lipid driven chronic inflammatory disease that is characterized by the formation of plaques at predilection sites. These predilection sites (side branches, curved segments, and bifurcations) have often been associated with disturbed sh ...

ELSEVIER SCI LTD2021

Following spatial A beta aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics

Anders Meibom, Stéphane Laurent Escrig, Melissa Kathleen Passarelli

beta-Amyloid (A beta) plaque formation is the major pathological hallmark of Alzheimer's disease (AD) and constitutes a potentially critical, early inducer driving AD pathogenesis as it precedes other pathological events and cognitive symptoms by decades. ...

AMER ASSOC ADVANCEMENT SCIENCE2021

Predicting future myocardial infarction from angiographies with deep learning

Pascal Frossard, Emmanuel Abbé, Olivier Muller, Ortal Yona Senouf, Thabodhan Mahendiran, Stéphane Fournier, Omar Raita, David Meier, Nicolas Dayer, Farhang Aminfar

In patients with stable Coronary Artery Disease (CAD), the identification of lesions which will be responsible of a myocardial infarction (MI) during follow-up remains a daily challenge. In this work, we propose to predict culprit stenosis by applying a de ...

2021

Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Andreas Pitzschke, Manish Jain, Ying Xiao

Although the versatility of photodynamic therapy (PDT) is well established, the technical aspects of light delivery systems vary significantly depending on the targeted organ. This article describes the optical properties of a light and drug delivery syste ...

2020

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Atheroma

Spatial analysis of 10-year predicted risk and incident atherosclerotic cardiovascular disease: the CoLaus cohort

Combining European and US risk prediction models with polygenic risk scores to refine cardiovascular prevention: the CoLaus|PsyCoLaus Study

Impact and implications of mixed plaque class in automated characterization of complex atherosclerotic lesions

Sub-micrometer morphology of human atherosclerotic plaque revealed by synchrotron radiation-based mu CT-A comparison with histology

Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons Living With HIV: The Swiss HIV Cohort Study

Considerations for analysis of endothelial shear stress and strain in FSI models of atherosclerosis

Following spatial A beta aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics

Predicting future myocardial infarction from angiographies with deep learning

Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque

Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression

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Spatial analysis of 10-year predicted risk and incident atherosclerotic cardiovascular disease: the CoLaus cohort

Impact and implications of mixed plaque class in automated characterization of complex atherosclerotic lesions

Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression

Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons Living With HIV: The Swiss HIV Cohort Study

Sub-micrometer morphology of human atherosclerotic plaque revealed by synchrotron radiation-based mu CT-A comparison with histology

Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque

Combining European and US risk prediction models with polygenic risk scores to refine cardiovascular prevention: the CoLaus|PsyCoLaus Study

Following spatial A beta aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics

Considerations for analysis of endothelial shear stress and strain in FSI models of atherosclerosis

Predicting future myocardial infarction from angiographies with deep learning