Concept

Macular degeneration

Related publications (115)

Pattern Dystrophy With High Intrafamilial Variability Associated With Y141C Mutation In The Peripherin/Rds Gene And Successful Treatment Of Subfoveal Cnv Related To Multifocal Pattern Type With Anti-Vegf (Ranibizumab) Intravitreal Injections

Objective: To identify disease causing mutation in three generations of a Swiss family with pattern dystrophy and high intrafamilial variability of phenotype. To assess the effect of intravitreal ranibizumab injections in the treatment of subfoveal choroid ...

Lippincott Williams & Wilkins2012

Anti-angiogenic treatment for exudative age-related macular degeneration: new strategies are underway

Patrycja Nowak-Sliwinska

Exudative age-related macular degeneration (AMD) is the leading cause of blindness in elderly people in the western world. Recent developments in the field yielded vascular endothelial growth factor (VEGF) targeted strategies that caused a revolution in th ...

2012

Early apoptosis of rod photoreceptors in Rpe65(-/-) mice is associated with the upregulated expression of lysosomal-mediated autophagic genes

RPE65-related Leber's congenital amaurosis (LCA) is a rod-cone dystrophy whose clinical outcome is mainly attributed to the loss of rod photoreceptors followed by cone degeneration. Pathogenesis in Rpe65-/- mice is characterized by a slow and progressive d ...

2012

Angiogenesis inhibition for the improvement of photodynamic therapy: The revival of a promising idea

Hubert van den Bergh, Patrycja Nowak-Sliwinska

Photodynamic therapy (PDT) is a minimally invasive form of treatment, which is clinically approved for the treatment of angiogenic disorders, including certain forms of cancer and neovascular eye diseases. Although the concept of PDT has existed for a long ...

2012

Organic electronics allows the photo-electric excitation and inhibition of neuronal activity in primary neuronal cultures and acute retinal explants

Diego Ghezzi

Interfacing organic electronics and biology offers new possibilities in biotechnology, due to the unique properties exhibited by organic conducting polymers (e.g. biological affinity, mechanical flexibility, ease of functionalization and cost effectiveness ...

2012

Organic electronics allows the photo-electric excitation of neuronal activity in primary neuronal cultures and acute retinal explants

Diego Ghezzi

2012

Organic electronics allows the photo-electric excitation and inhibition of neuronal activity in primary neuronal cultures and acute retinal explants

Diego Ghezzi

Interfacing organic electronics and biology offers new possibilities in biotechnology, due to the unique properties exhibited by organic conducting polymers (e.g. biological affinity, mechanical flexibility and ease of functionalization). OCP have been exp ...

2012

Reflectance imaging of the human retina at 810 nm does not suffice to optimize the parameters of hydrodynamic rebalancing laser treatment

Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Filippo Piffaretti

The hydrodynamic rebalancing laser (HRL) procedure is an ophthalmic therapy based on the administration of subthreshold infrared (810 nm) laser light to selected areas on the retina to treat various retina diseases. Heterogeneities of tissue response are o ...

Spie-Soc Photo-Optical Instrumentation Engineers2012

Microalgal carotenoid recovery in a biorefinery approach

Christof Holliger, Christian Ludwig, Jean-Paul Schwitzguebel, Mariluz Bagnoud, Olivier Laurent Emery

Introduction Microalgae culture to be effective as feedstock for bio-energy production needs to overcome constraining biotechnological, technological and economic factors [1]. In order to establish an economically viable process, the co-production of renew ...

2012

Angiostatic kinase inhibitors to sustain photodynamic angio-occlusion

Hubert van den Bergh, Patrycja Nowak-Sliwinska, Blaise Lovisa

Targeted angiostatic therapy receives major attention for the treatment of cancer and exudative age-related macular degeneration (AMD). Photodynamic therapy (PDT) has been used as an effective clinical approach for these diseases. Since PDT can cause an an ...

2012

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