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Essential in biomedical research is the necessity of gathering statistically relevant data about large populations of specific biological entities, e.g. organisms, cells or molecules, while preserving detailed information about each single entity under in ...
Adverse conditions during fetal life have been associated to both structural and functional changes in neurodevelopment from the neonatal period to adolescence. In this study, connectomics was used to assess the evolution of brain networks from infancy to ...
Dynamical Systems (DS) are often used to represent motion, with the advantage of being easy to learn from demonstrations. We present a method to modulate DS depending on an external signal, extending our previous work on Locally Modulated DS (LMDS, Kronand ...
Developmental enhancers initiate transcription and are fundamental to our understanding of developmental networks, evolution and disease. Despite their importance, the properties governing enhancer-promoter interactions and their dynamics during embryogene ...
The development of visual functions is very diverse. Some visual functions mature within the first year of life, whereas maturation for other functions extends into adolescence. The reasons for these developmental differences are largely unknown. Here, we ...
The occurrence of chronic or delayed toxicity resulting from the exposure to sublethal chemical concentrations is an increasing concern in environmental risk assessment. The Fish Embryo Toxicity (FET) test with zebrafish provides a reliable prediction of a ...
Rhythmic and sequential segmentation of the embryonic body plan is a vital developmental patterning process in all vertebrate species. However, a theoretical framework capturing the emergence of dynamic patterns of gene expression from the interplay of cel ...
Perinatal Asphyxia is causing the death of about 1.2 million newborn infants every year. It is one of top three causes of infant mortality in developing countries. The current way of determining the occurrence of perinatal asphyxia is by the analysis of a ...
Infancy is a critical period for brain development. Emerging evidence indicates that stress experienced during that period can have long-term programming effects on the brain and behavior. However, whether different time periods represent different vulnera ...
Among the symptoms of schizophrenia, deficits in the recognition of intention is one of the most studied. However, there is no cognitive model of intention recognition that takes into account both innate and environmental/developmental factors. This work p ...