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Peroxisome proliferator-activated receptors (PPARs) have been revealed as key regulators of several skin disorders. This has led to a growing interest in the development of drugs targeting PPARs as therapeutics for skin diseases. To evaluate skin PPAR acti ...
An in vitro model, designated the Simulator of the Human Intestinal Microbial Ecosystem (SHIME), was used to study the effect of a soygerm powder rich in beta-glycosidic phytoestrogenic isoflavones on the fermentation pattern of the colon microbiota and to ...
An intercomparison of the performances of active neutron detectors was carried out in pulsed neutron fields in the new HiRadMat facility at CERN. Five detectors were employed: four of them (two ionization chambers and two rem counters) are routinely employ ...
An intercomparison of the performances of active neutron detectors was carried out in pulsed neutron fields in the new HiRadMat facility at CERN. Five detectors were employed: four of them (two ionization chambers and two rem counters) are routinely employ ...
The major components of soybean flour (ie, proteins, fibres, and isoflavones) have been investigated as possibly responsible for the cholesterol-lowering effects of soy-based diets. The evidence for and against the involvement of each component is reviewed ...
The class B scavenger receptor CD36 is a component of the pattern recognition receptors on monocytes that recognizes a variety of molecules. CD36 expression in monocytes depends on exposure to soluble mediators. We demonstrate here that CD36 expression is ...
The development of atherosclerosis is often associated with altered concentrations of systemic lipoproteins, which are determined by the concentration and/or activity of three groups of different proteins, i.e. apolipoproteins (apo), enzymes, and receptors ...
Methods and compositions are provided for treating a host having a gastrointestinal (GI) disease by administering to the host a composition containing a pharmaceutically effective amount of a modulator of a Peroxisome Proliferator Activated Receptor (PPAR) ...
Research on endocrine disruption in fish has been dominated by studies on estrogen-active compounds which act as mimics of the natural estrogen, 17 beta-estradiol (E2), and generally exert their biological actions by binding to and activation of estrogen r ...
White adipose tissue (WAT) can differentiate into beige adipose tissue by the browning process. Some polyphenols, including isoflavones, particularly genistein, are suggested to increase the expression of browning markers. There is evidence that consumptio ...
