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Covers challenges in protein design, energy functions, search algorithms, and applications in synthetic biology, emphasizing the importance of protein design and the methods used for designing proteins.
Explores protein structure determination through X-ray crystallography, NMR spectroscopy, and Cryo-EM, covering crystallization, diffraction patterns, and atomic models.
Delves into protein folding principles, emphasizing sequence's role in determining structure and exploring thermodynamics and intermolecular interactions.
Explores protein design challenges, validation through crystallography, evolution of design techniques, and the difference between genetic and protein circuits.
Covers the process of expressing and purifying proteins, including the importance of studying protein function, folding, interactions, sequence, and structure.
