Concept

Movement disorder

Related publications (32)

Loss of Motor Cortical Inputs to the Red Nucleus after CNS Disorders in Nonhuman Primates

The premotor (PM) and primary motor (M1) cortical areas broadcast voluntary motor commands through multiple neuronal pathways, including the corticorubral projection that reaches the red nucleus (RN). However, the respective contribution of M1 and PM to co ...

SOC NEUROSCIENCE2023

Fast-Spiking Interneurons of the Premotor Cortex Contribute to Initiation and Execution of Spontaneous Actions

Silvestro Micera, Maria Pasquini

Planning and execution of voluntary movement depend on the contribution of distinct classes of neurons in primary motor and premotor areas. However, timing and pattern of activation of GABAergic cells during specific motor behaviors remain only partly unde ...

SOC NEUROSCIENCE2023

Modeling spinal locomotor circuits for movements in developing zebrafish

Yann Roussel

Many spinal circuits dedicated to locomotor control have been identified in the developing zebrafish. How these circuits operate together to generate the various swimming movements during development remains to be clarified. In this study, we iteratively b ...

eLIFE SCIENCES PUBL LTD2021

Gait analysis in children with cerebral palsy: bridging the gap between the laboratory and real life

Lena Carcreff

Like 17 million people worldwide, an individual with cerebral palsy (CP) does not have the opportunity to walk harmoniously in society due to long-life impairments in movement and posture. The natural course of CP can be modulated by treatments and therapi ...

EPFL2020

Spatio-temporal structure of single neuron subthalamic activity identifies DBS target for anesthetized Tourette syndrome patients

Silvestro Micera, Matteo Vissani

Objective. Deep brain stimulation (DBS) of basal ganglia effectively tackles motor symptoms of movement disorders such as Tourette syndrome (TS). The precise location of target stimulation site determines the range of clinical outcome in DBS patients, and ...

IOP PUBLISHING LTD2019

Functional imaging of rostrocaudal spinal activity during upper limb motor tasks

Dimitri Nestor Alice Van De Ville, Silvestro Micera, Elvira Pirondini, Nawal Noëlle Kinany, Roberto Martuzzi

The spinal cord is the main interface between the brain and the periphery. It notably plays a central role in motor control, as spinal motoneurons activate skeletal muscles involved in voluntary movements. Yet, the spinal mechanisms underlying human moveme ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

Functional imaging of rostrocaudal spinal activity during upper limb motor tasks

Dimitri Nestor Alice Van De Ville, Silvestro Micera, Elvira Pirondini, Nawal Noëlle Kinany, Roberto Martuzzi

2019

Reverse engineering the motor control system

Berat Denizdurduran

Mammalian motor control is implemented by a combination of different networks and system, working coherently to plan the movement of the body or a limb and to execute this movement a dynamical environment. While it is believed that complex, voluntary movem ...

EPFL2019

e-Glass: A Wearable System for Real-Time Detection of Epileptic Seizures

David Atienza Alonso, Amir Aminifar, Dionisije Sopic

Today, epilepsy is one of the most common chronic diseases affecting more than 65 million people worldwide and is ranked number four after migraine, Alzheimer’s disease, and stroke. Despite the recent advances in anti-epileptic drugs, one-third of the epil ...

2018

Brain-controlled modulation of spinal circuits improves recovery from spinal cord injury

Silvestro Micera, Grégoire Courtine, Marco Bonizzato, Polina Shkorbatova, Natalia Pavlova, Galyna Pidpruzhnykova

The delivery of brain-controlled neuromodulation therapies during motor rehabilitation may augment recovery from neurological disorders. To test this hypothesis, we conceived a brain-controlled neuromodulation therapy that combines the technical and practi ...

Nature Publishing Group2018

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