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Lecture
Are you an EPFL student looking for a semester project?
Work with us on data science and visualisation projects, and deploy your project as an app on top of Graph Search.
This lecture covers the electron transport chain in mitochondria, focusing on the oxidation of NADH, the role of cytochromes, and the creation of an electrochemical gradient. It explains how this gradient drives ATP synthesis through ATP synthase, detailing the process of oxidative phosphorylation and the importance of the citric acid cycle. The lecture also discusses the respiratory chain of electron carriers, the function of different complexes, and the final step of electron transfer to oxygen. Additionally, it explores the creation and utilization of the electrochemical H+ gradient, highlighting its significance in ATP production. The mitochondrial ATP synthase mechanism is explained, emphasizing the role of proton flow in generating mechanical energy for ATP synthesis.