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This lecture covers the three stages of catabolism of proteins, fatty acids, and carbohydrates, focusing on the electron transport chain and oxidative phosphorylation in mitochondria. It explains the role of NADH and FADH2 in reducing oxygen to water, producing ATP. The lecture also details the structure and function of the mitochondrial compartments, including the inner and outer membranes, cristae, and matrix. It discusses the electron transport chain complexes I-IV, the role of Coenzyme Q, Cytochrome c, and the process of ATP synthesis by ATP synthase. Additionally, it explores iron-sulfur clusters, reactive oxygen species, and the Q cycle in Complex III.