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This lecture covers the principles of mastery learning, focusing on classical conditioning as demonstrated by Ivan Pavlov. It explains the process of conditioning, from the unconditioned stimulus to the conditioned response, with examples and applications. The lecture also delves into the Law of Effect by Edward Thorndike, emphasizing the importance of immediate feedback in learning. It explores behaviorism concepts, such as operant conditioning by B.F. Skinner, and the use of intelligent tutoring systems for personalized instruction. The lecture concludes with the implementation of mastery learning through prerequisite tests, remediation, and adaptive testing, ensuring a deeper understanding of the material.