Explores the molecular chaperone action of small heat shock proteins in proteostasis, focusing on their interaction with misfolded proteins and amyloid fibrils.
Explores the conformational and functional flexibility of Hsp70 molecular chaperones, focusing on folding intermediates and the Hsp70 functional cycle.
Covers the basics of polymer biophysics, including DNA conformation modeling and the Boltzmann principle, emphasizing the exponential decay of correlations between segments.
Explores Heat Shock Transcription Factors' regulation and targets in response to stress, including HSF2's dynamic expression and impact on cell adhesion.
