DNA Repair Mechanisms

This lecture covers the intricate process of DNA repair mechanisms, focusing on the excision repair pathway and the role of various enzymes in repairing DNA lesions induced by factors like UV radiation. The instructor explains the sequential actions of endonucleases, DNA polymerases, and ligases in excising damaged DNA segments and synthesizing new DNA strands. The lecture also delves into the correction of base mismatches and the repair of single-strand and double-strand breaks caused by ionizing radiation. The importance of maintaining genetic integrity through efficient DNA repair mechanisms is emphasized, showcasing the complex yet vital processes that safeguard the genetic material in cells.