Lecture

Chemical Biology Toolsets: Enzyme Inhibition and Target Modulation

Description

This lecture covers the chemical biology toolsets related to enzyme inhibition, including reversible (competitive, non-competitive, TS analog) and irreversible mechanisms. It also discusses small-molecule-based target modulation techniques like the Bump-Hole method and ABPP indirect profiling. Additionally, it explores transcriptome/genome-probing tools such as mRNA display and RNA aptamers. The lecture delves into proteome-level probing tools like the Amber suppressor technique and SILAC-BONCAT method, highlighting their applications in chemical biology.

This video is available exclusively on Mediaspace for a restricted audience. Please log in to MediaSpace to access it if you have the necessary permissions.

Watch on Mediaspace

Instructor

Velit Lorem reprehenderit aliquip amet id do do quis mollit nostrud non proident. Ut cillum sunt dolore proident eiusmod excepteur do irure. Minim eu ullamco velit commodo elit incididunt id dolore deserunt cupidatat. Sint do occaecat magna duis duis quis ad irure nulla dolore elit voluptate. Commodo nostrud aliqua aute qui ex est sint quis voluptate dolore aliquip labore nisi veniam.

Official source

https://mediaspace.epfl.ch/media/0_58lv6nwn

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Ontological neighbourhood

Biology

Cell biology: Metabolism, Protein biosynthesis

Genetics: Genomics

Related lectures (144)

Graph Chatbot

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.