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This lecture covers the structure and function of ion channels, membrane proteins with water-filled pores that are permeable to ions. It explains the classification of ion channels based on gating and main ion specificity, highlighting the importance of these channels in various physiological processes. The lecture also delves into membrane permeability, ion channel function, classification systems, and the role of ion channels in single-cell activities. Additionally, it discusses the impact of toxins on ion channels and the biophysical models governing ionic currents.