Lectures related to Designing Targeted Protein Degraders

Molecular machines involved in mycobacterial protein quality control pathways

Explores molecular machines in mycobacterial protein quality control pathways, focusing on degradation, proteases, and pupylation-dependent degradation.

Regulation Mechanisms Overview

Covers phosphorylation, ubiquitinylation, methylation, and more in biological regulation.

Protein Maturation: Post-Translational Modifications

Covers the maturation of proteins and the role of post-translational modifications in their functionality and regulation.

Protein Quality Control of Membraneless Organelles

Explores protein quality control in membraneless organelles and its implications for diseases.

Bacterial AAA+ Protease: Activity Control and Toxic Deregulation

Explores the activity control and toxic deregulation of a bacterial AAA+ protease, focusing on the role of AAA+ machines in protein quality control.

The ClpXP Proteolytic Complex: Basic Principles to Drug Discovery

Explores the ClpXP proteolytic complex, its drug targeting potential, and antimicrobial applications through compound screening.