Metabolism and Hormones

This lecture covers the specific metabolism of tissues, focusing on the division of labor among organs such as the pancreas, liver, brain, adipose tissue, and skeletal muscle. It explains how hormones like insulin and glucagon regulate metabolism through signaling pathways, enzyme cascades, and the synthesis of energy-related hormones. The lecture also delves into the effects of insulin and glucagon on blood glucose levels, glycogenolysis, gluconeogenesis, ketogenesis, and lipolysis. Additionally, it explores the production and distribution of insulin and glucagon in the pancreas, the synthesis and maturation of insulin, and the mechanisms of insulin action in glucose uptake and storage. The regulation of enzymes in intermediary metabolism by phosphorylation mechanisms is also discussed.