Retinoblastoma: Genetic Mechanisms and Clinical Implications

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Covers the basics of genetics, inheritance of alleles, genotype-phenotype relationship, and population genetics.

Explores the impact of mutations on disease development and the importance of genetic variability in medicine.

Explores genetic and epigenetic changes in cancer, including mutations, chromosomal alterations, and high-throughput measurement methods.

Explores the multi-step progression of tumors, from cancer incidence rates to tumor initiators and promoters.

Explores DNA methylation analysis and gene mutations in Angelman Syndrome.

Explores the biological effects of ionizing radiation and how tissues defend against damage.

Provides an overview of translation and protein synthesis, covering the genetic code, tRNA, and the steps involved in protein formation.

Explores mutations, genetic diversity, and horizontal gene transfer, emphasizing the impact of errors during replication and exposure to mutagens.

Explores mutations and polymorphisms, highlighting their impact on genetic diversity.

Explores DNA replication accuracy mechanisms, including proofreading by DNA polymerase.