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This lecture introduces the concept of Cell Engineering, focusing on Protein Circuit Design as a key aspect of synthetic biology. It explores the goals of engineering intelligent cells, the functionalities needed, and the design considerations for genetic and protein circuits. The lecture covers the challenges and advantages of using proteins in circuit design, the components of ideal protein circuits, and the different layers involved in engineered protein systems. It also discusses the limitations of current sensing schemes and the strategies for improving signal transmission in synthetic biological systems.
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