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This lecture delves into the design of protein circuits, focusing on the recent advancements in synthetic biology. The instructor discusses the critical questions, challenges, and ongoing research in the field, emphasizing the importance of engineering cells to manipulate and understand cellular functions. The lecture covers the concepts of sensing, processing, and actuation within cells, exploring the design of protein circuits for various applications, such as immune cell therapy and chemical factories. The discussion includes examples of engineered protein interactions, the use of scaffolding proteins for signal transmission, and the potential of protein design in creating versatile and specific binding interactions.
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