This lecture introduces the organization of the course, including weekly exercises and discussion sessions. It covers the composition and structure of proteins, protein synthesis, and the exploration of genes and genomes. The lecture delves into the ionization state of amino acids, the strengths of molecular interactions, and the classes of biomolecules. It explains the significance of pH, the state of ionization of functional groups, and the role of side chains in protein structure. The session also discusses the formation of disulfide bridges and the primary structure of proteins.